Susan Hasty, Publisher
Table of Contents . . . October 17th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications
Avian Influenza Vaccine - Vaccine development for potential avian influenza pandemic reviewed
Diagnostics - Proteomic pattern diagnostics has potential for diagnostics development
Diet and Nutrition - Dietary supplement use by U.S. adults reported
Hemorrhagic Fever - Ngari virus associated with outbreaks of hemorrhagic fever in Africa
Obesity Survival and Mortality - Methods of calculating deaths attributable to obesity compared
AIDS/HIV Therapy - Effort underway to improve the quality of HIV care in U.S.
AIDS/HIV Vaccine - Breakthrough infections occur during HIV-1 vaccine trials
AIDS/HIV Vaccine - Development of AIDS vaccine from South African perspective presented
AIDS/HIV Vaccine - Program changes needed to introduce vaccines targeted at adolescents
Anthrax - DNA-based anthrax vaccine generates antibodies in rabbits in challenge study
Anthrax Vaccine - Murine model of pulmonary anthrax described
Antibiotics - Pharma company recieves tentative FDA approval for Levoflozacin tablets
Anticoagulants - FDA committee wants more data to support approval of Exanta
Arthritis - VIOXX maker withdraws drug from market
Asthma Therapy - Monitoring response to treatment in asthma management reviewed
Autoimmune Disease - Distribution of pulmonary surfactant protein A in tissues is regular
Avian Influenza - U.S. may buy experimental bird flu vaccine
Bioterrorism - Bacterial genomics company secures defense research grant
Breast Cancer - Cigarette smoke condensate induces transformation of normal breast cells
Breast Cancer Risk Factor - Polychlorinated biphenyls and breast cancer risk ambiguous
Breast Cancer Risk Factor - Role of organochlorines in breast cancer carcinogenesis uncertain
Breast Implants - Settlement awards $11.3 million to U.S. government for Medicaid expenses
Cancer Therapy - AMD3100 to advance to phase III for stem cell transplant in cancer patients
Cancer Therapy - Novel antimetabolite exhibits antitumor activity in FU-resistant cancer
Cancer Therapy - Studies suggest alternatives to surgery needed in treatment of head, neck cancer
Cancer Vaccine - Proteasomal cleavage does not determine gp100 peptide immunogenicity
Cholera Vaccine - TcpA subunit induces IgA immune responses in patients with cholera
Clinical Trials - Drug company awarded phase 1 study worth $1.5 million in cardiac services
Clinical Trials - Enrollment begun in phase 3 clinical trial of Glufosfamide for pancreatic cancer
Clinical Trials - Oncology group participating in clinical trial of women with breast-brain cancer
Collaborations - Oral interferon rights licensed to Nobel to treat Behcet disease
Colon Cancer - Beta-catenin expression related to pit pattern in colorectal cancer
Colorectal Cancer - Newsletters, videos might cut cancer in churchgoing blacks
Complementary and Alternative Medicine - Exercise-induced syncope associated with ephedra-free xenadrine
Complementary and Alternative Medicine - Fatal hepatic failure possibly induced by nitrosofenfluramine reported
Creutzfeldt-Jakob Disease - vCJD epidemic estimated at 150-500 deaths if 11-15 year incubation period
Defibrillator - FDA clears HeartStart home defibrillator for over-the-counter sale
Depression - Treatment IDE submitted for VNS therapy
Depression - Two experts evaluate suicide risk with antidepressants
Diagnostics - FDA approves Second Look Digital CAD software for use with Hologic's FFDM
Diagnostics - Fluorescent probes can be used to examine intracellular organelle function
Disease Prevention - Senate committee approves funding for new U.S. CDC lab in Colorado
Distribution Agreement - Dynatronics named master distributor for IontoPlus electrodes
Domestic Violence - Emergency department-based screening project begins in Atlanta
Drug Delivery - Biopharma company announces license termination agreement with Pfizer
Drug Development - Biotech company updates progress of split flu vaccine production in China
Drug Development - Dopamine depletor for chorea receives FDA 'fast track' designation
Drug Development - Drug company in-licenses Alzheimer drug from Georgetown for further development
Drug Development - Pharma company preparing application for phase III study of muscle relaxant
Drug Development - Pharmaceuticals company reports on filing, approval of ANDAs with the FDA
Encephalitis Vaccine - Immunity after tick-borne encephalitis vaccination is persistent
Endometrial Cancer - Letrozole has limited activity in advanced endometrial cancer
Environmental Health - Washington representative says EPA is short on details of dredging plans
Epidemiology - Studies point to a pathophysiological basis for atherogenic potential of arsenic
Feline Virus Infection - Viral infection outbreaks seen in cats in Wroclaw city area in Poland
Filariasis Vaccine - Subtractive screening identifies Brugia malayi vaccine candidates
Filtration - CCAT awards EFP grant to begin nano-enhanced filter media test for U.S. military
Finance - CDC funding to develop TB vaccine trial sites in India
Finance - Company raises $7M from sale of common stock
Food Additive - FDA accepts adenosine monophosphate safety status
Fungal Infection - Company changes name of serum test
Gene Profiling - Antiangiogenic agents stimulate gene expression changes early on
Generic Drugs - FDA accepts NDA filing for megestrol acetate oral suspension NCD
Glanders - Scientists decipher genetic code of biothreat pathogen
Global Health - Combining TB treatment, HIV testing and treatment could save many African lives
Global Health - Fractures mean broken lives in developing world
HIV/AIDS Epidemiology - AIDS epidemic poses serious threat to Europe
HIV/AIDS Prevention - AIDS prevention programs can be transferred to developing countries
HIV/AIDS Research - Decreased T-cell proliferation is central in CD4 cell expansions induced by IL-2
HIV/AIDS Therapy - Access to HAART increasing in Thailand
Heart Disease - Rinspiration System receives FDA clearance for coronary, peripheral use
Heart Disease Risk - Abused, neglected children more likely to have heart disease as adults
Hepatitis B Vaccine - Hepatitis B prevalent despite vaccination programs in Pacific Islands
Hepatitis C Virus - Ovine atadenovirus induces strong T cell response against hepatitis C
Imaging - FDA gives Xplorer 1600 clearance
Immunology - Seventeen-color flow cytometry provide insights into immune system
Immunology - Type 1 and type 2 immunity in healthy Japanese adults assessed
Infection - Pharmaceutical company receives FDA approval to market ciprofloxacin tablets
Infectious Disease - In natural disasters, cadavers pose no threat of disease
Influenza - Recent advances in development of anti-influenza drugs reviewed
Information Technology - Company announces safety-critical platform for embedded medical devices
Legal Issues - Molecular diagnostics company files patent infringement suit against Stratagene
Leishmaniasis Vaccine - Intranasal vaccine protects against cutaneous leishmaniasis
Malaria - Genomics of innate immunity in malaria vector reviewed
Malaria Vaccine - Analogue of epitope from malaria vaccine protein characterized
Malaria Vaccine - Conserved region of P. falciparum targeted by antibodies identified
Malaria Vaccine - Effect of natural selection in malaria parasites discussed
Malaria Vaccine - Long-term T-cell responses induced by Plasmodium peptides
Malaria Vaccine - PfEMP1-DBL1 alpha antibodies protect Plasmodium falciparum
Melanoma Therapy - Curcumin plus tumor-related proteins inhibited growth of melanoma cells
Menopause - FDA issues approvable letter for ANGELIQ
Multiple Sclerosis - New immunosuppressants to treat multiple sclerosis developed
Myopia - FDA approves Artisan / Verisyse phakic intraocular lens
Nanotechnology - Grant award to fund NanoReader device to target detection of whole viruses
Narcolepsy - CNS pharma company announces clinical results for narcolepsy treatment
Nearsightedness - FDA approves Verisyse implantable lens
Neural Tube Defects - Fortifying food with folic acid benefits babies
Neurogenesis - Alproate promotes ERK pathway-dependent cortical neuronal growth/neurogenesis
Nicotine Vaccine - Ethics of nicotine conjugate vaccine discussed
Pain Medicine - Company provides update on status of oxymorphone program
Panencephalitis - Prevalence of sclerosing panencephalitis in Chinese children reported
Pediatric Practice - More medical devices needed for babies
Pneumococcal Disease - CDC recommends return to full four-dose series of Prevnar
Pneumonia - Oral amoxicillin could be future treatment for children in developing countries
Preparedness - Guide helps communities prepare for vaccine and drug dispensing
Psychotropic Drugs - Licensing agreement for triple uptake inhibitors for depression clears hurdle
Rectal Cancer - Radio-resistance-related proteins in rectal cancer reviewed
Regulatory Issues - Company responds to FDA recommendations on antidepressants in children, teens
Reovirus Vaccine - Dendritic cells process viral antigen from apoptotic epithelial cells
Respiratory Syncytial Virus - Recombinant respiratory syncytial virus with deletion characterized
Rosacea - Col-101 for rosacea to be dubbed "Oracea"'
Rotavirus - Group C rotavirus outbreak affected infants and children in Maizuru city
SARS - Aurintricarboxylic acid inhibits SARS coronavirus replication
SARS Vaccine - Advancements in the battle against severe acute respiratory syndrome
SARS Vaccine - Neutralizing monoclonal antibodies to SARS-coronavirus characterized
Sepsis - Cytokine is potential therapeutic target for septic patients
Sexually Transmitted Disease - Sexually transmitted diseases and managed care reviewed
Sleep Apnea - FDA clears implantable medical device as treatment for sleep apnea
Spinal Cord Injury - Spinal cord injury therapy granted FDA orphan drug designation
Streptococcus Vaccine - Maternal streptococcus antibody correlates with neonate protection
Supplements - Chromium picolinate safety data presented at CDC conference
Tula Virus - Tula virus strains from Poland closely related to TULV from elsewhere in Europe
Urban Health - Chinese study finds most city dwellers in poor health, educated most at risk
Vaccine Development - Current status and future directions of cell processing reviewed
Vaccinia Virus - A13 phosphoprotein required for assembly of mature vaccinia virions
Vascular Disease - Vascular repair and regeneration is regulated by bone-marrow derived cells
Water-Borne Illness - WHO issues revised drinking water guidelines
West Nile Fever - Factors related to West Nile control in British Columbia discussed
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