Cancer Vaccine
Proteasomal cleavage does not determine gp100 peptide immunogenicity
Published in Medical Letter on the CDC and FDA, October 17th, 2004
According to a study from the United States, "Immune responses against tumor-associated antigens rely on efficient epitope presentation. The melanoma-associated antigen gp100 contains HLA-A*0201 ligands that are characterized by low to medium binding affinity, among which gp100209-217 is the most prominent. While this epitope is a natural T-cell target, it primes with low-efficiency T-cell responses during immunization. A modified gp100 epitope, gp100209-217T210M , that contains a Thr to Met substitution at...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Medical Letter on the CDC and FDA
More Articles from Medical Letter on the CDC and FDA
- Avian Influenza Vaccine
Vaccine development for potential avian influenza pandemic reviewed - Diagnostics
Proteomic pattern diagnostics has potential for diagnostics development - Diet and Nutrition
Dietary supplement use by U.S. adults reported - Hemorrhagic Fever
Ngari virus associated with outbreaks of hemorrhagic fever in Africa - Obesity Survival and Mortality
Methods of calculating deaths attributable to obesity compared - AIDS/HIV Therapy
Effort underway to improve the quality of HIV care in U.S. - More from this issue of Medical Letter on the CDC and FDA
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
