Neuroscience
Magnocellular neuron gene expression determined in supraoptic nucleus
Published in Medical Letter on the CDC and FDA, October 24th, 2004
Oxytocin- and vasopressin-producing MCNs "of the hypothalamo-neurohypophysial system are the only neuronal phenotypes present" in the rat SON, according to scientists in the United States.
"Laser microdissection of the SON, extraction and T7-based amplification of its RNAs, and analysis of the resulting cDNAs by hybridization on a 35, 319 element DNA microarray, have provided a detailed composite view of the gene expression profile of the MCNs," reported N. Mutsuga and colleagues at the National Institute of Neurological Disorders and...
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