Hepatocellular Carcinoma
Gene expression patterns with prognostic value identified
Published in Medical Letter on the CDC and FDA, November 7th, 2004
In a recent study, hepatologists in the United States, "analyzed global gene expression patterns" of 91 human HCCs "to define the molecular characteristics of the tumors and to test the prognostic value of the expression profiles."
"Unsupervised classification methods revealed two distinctive subclasses of HCC that are highly associated with patient survival," reported J.S. Lee and coauthors at the National Cancer Institute. "This association was validated via five independent supervised learning methods."
"We also identified the...
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