Medical Letter on the CDC and FDA

AIDS/HIV Therapy - Providers in Brazil following guidelines for management of HIV patients

Ebola Virus - Blood samples from fatal and nonfatal cases of Ebola infection analyzed

Environmental Health - Metabolite of pesticide methoxychlor reduces testosterone formation

Hepatitis B - Outbreak of hepatitis B in drug users causes high mortality

Sexually Transmitted Disease - Internet Alert Project spreads word about high-risk sexual activities

AIDS/HIV Transmission - Model of perinatal transmission of SHIV in macaques developed

AIDS/HIV Vaccine - HIV-1 Tat protein modulates generation of cytotoxic T cell epitopes

AIDS/HIV Vaccine - HIV-1 Tat vaccine protects against SHIV89.6P replication in monkeys

AIDS/HIV Vaccine - nef-deleted SHIV protects against pathogenic virus infection

Acne - U.S. FDA approves Evoclin for treating acne

Alzheimer Disease - Pharma company files amendment for urine NTP test kit

Anthrax Vaccine - Plasmid DNA vaccine protects against aerosolized anthrax spores

Anthrax Vaccine - Vaccine protects cheetah and black rhinoceros against anthrax

Antibiotic Resistance - Antibiotics use alliance report reveals urgency of drug resistance worldwide

Atrial Fibrillation - CryoBlator approved for use in U.S. trials, CE marked in Europe

Avian Influenza - Data shows Tamiflu is effective against human H5N1 and avian H5N1 influenza

Bacterial Resistance - Indian Salmonella Typhi isolates have reduced ciprofloxacin susceptibility

Bacteriology - High-throughput method for counting bacterial colonies developed

Basal Cell Carcinoma - Basal cell carcinoma rates continuously increasing in the Netherlands since 1973

Brain Tumor - FDA grants priority review status for brain tumor drug; EMEA application made

Breast Cancer - Femara gets U.S. FDA nod as post-tamoxifen treatment for early breast cancer

Breast Cancer - New breast exam recommendations issued

Breast Implants - Connective tissue disorder risk in breast implant patients re-assessed

Breast Implants - System lowers breast augmentation re-operation rate by 17%

Business & Finance - Medical oncology device company announces third quarter, 9-month results

Cancer Research - Pharma company offers data on Yondelis and Aplidin at conference

Cancer Therapy - Company achieves commercial scale of antigen for Provenge

Cancer Therapy - U.S. FDA fast-tracks phenoxodiol for recurrent ovarian cancer

Canine Distemper Virus - DNA vaccine protects against lethal canine distemper virus challenge

Cardiovascular Disease - African American heart failure trial data submitted to the U.S. FDA

Cardiovascular Disease - Pharma company granted rights to thrombolytic agent, names executives

Central Nervous System Disease - Stem cell focused biotech completes equity financing to support clinical trial

Cigarette Smoke - Low levels of cigarette smoke induce irreversible change in cell chromosomes

Clinical Trial - New data from hyponatremia treatment trials released

Clinical Trials - NDA for anticancer therapeutic drug submitted to U.S. FDA by two drug companies

Colon Cancer - U.S. FDA clears second stage of CoFactor phase II trial

Community-Associated Infection - Risk of community-associated MRSA infection is associated with several factors

Cytomegalovirus - T cell immunity to cytomegalovirus studied in HIV patients after HAART

Dengue Vaccine - Mutations in dengue virus vaccine candidate decreases virus replication

Developmental Toxicity - Developmental toxicity of water disinfection by-products appears to be additive

Diabetes Treatment - U.S. FDA gives nod to OTC use of insulin-dosing technology

Diagnostics - Method to measure perchlorate anion in foods by IC-MSMS developed

Diagnostics - Whole blood cytokine detection assay to quantitate T-cells developed

Diarrhea Epidemiology - Diarrhea episodes in slum area of north Jakarta, Indonesia, studied

Diarrhea Therapy - Preferences for treatment of diarrhea in China surveyed

Diarrhea Therapy - Self-treatment for diarrhea common in Vietnam

Dysentery Vaccine - Cultural context of dysentery has implications for vaccine introduction

Elispot - Influence of method and operator on Elispot results reviewed

Endoscopy - PillCam reported as accurate as EGD in visualizing esophagus abnormalities

Environmental Toxins - EPA seeks applicants for grants to investigate environmentally induced disease

Eye Health - Medical technology company granted marketing clearance for Lasik technology

Finance - Biopharmaceutical company reports loss of $0.22 per share

Finance - Medical imaging company reports $2.6 million loss in third quarter

Finance - Oncology-focused pharmaceutical co. reports third quarter financial results

Finance - Ophthalmic products producer reports improved third quarter financial results

Finance - Pharma company announces improved third quarter 2004 financial results

Finance - Pharmaceutical company announces revenues of $1M due to Plenaxis sales

Finance - Vision technology firm raises $9M, obtains protocol agreement for MelaFind

Gastric Ulcer - Biopharma company initiates phase II trial with TB4 for chronic pressure ulcers

Gastroesophageal Reflux Disease - Clinical trial results of nocturnal gastric acidity drugs comparison reported

Generic Drugs - Generic drug maker announces tentative approval of restosterone gel 1%

Generic Drugs - U.S. FDA approves ANDA for Citalopram hydrobromide tablets

Growth Hormone Deficiency - New indication for Norditropin approved by FDA

HIV/AIDS - Pharma company files application with FDA for antiretroviral agent

HIV/AIDS & Tuberculosis - Strategy developed to decrease global burden of TB/HIV

HIV/AIDS Diagnostics - Rapid field test sensitive and specific for detecting/differentiating HIV types

HIV/AIDS Prevention - WHO issues new online tool kit for sex workers

Healthcare Coverage - HHS approves Idaho request to help SCHIP families buy employer-based insurance

Hepatitis B - Britain should adopt universal hepatitis B immunization, says doctor

Hepatitis B - European authorities give positive opinion for Fendrix vaccine

Hepatitis B Virus - Trials show hepatitis B agent a statistical improvement in infected patients

Hepatitis C Virus - Peginterferon alfa-2B studies show positive data in treatment of hepatitis C

Herpesvirus - Pre-IND contact initiated with U.S. FDA for clinical trials of CY301 for herpes

Human Immunodeficiency Virus - Structure of anti-human immunodeficiency virus type 1 antibody 2F5 reported

Immunizations - Financial challenges of immunization reviewed