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Medical Letter on the CDC & FDA

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Adverse Drug Effects



Dinitrophenol-related fatality reported



December 12th, 2004

Researchers report a fatality related to dinitrophenol, a dietary weight loss aid.

According to recent research from the United States, "2,4-dinitrophenol (DNP) was originally used as an explosive and later introduced in the 1930's to stimulate metabolism and promote weight loss. It's also a component of pesticides still available globally. Concerns about hyperpyrexia lead to DNP being banned as a dietary aid in 1938."

"A 22-yold male presented to the emergency department with a change in mental status 16 hours after his last dose of DNP," said Robin B. McFee and colleagues at the Long Island Regional Poison Control Center. "On admission he was...


Source: Medical Letter on the CDC & FDA (2004-12-12)

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