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Anthrax Vaccine

Mass value for IgG in standard anthrax reference serum assigned

Published in Medical Letter on the CDC and FDA, December 12th, 2004

Scientists have assigned the mass values for total and subclass immunoglobulin G in a human standard anthrax reference serum.

According to recent research published in the journal Clinical and Diagnostic Laboratory Immunology, "An anti-anthrax vaccine adsorbed (anti-AVA) standard human reference serum pool, AVR414, has been prepared, and the total and protective antigen (PA)-specific immunoglobulin G (IgG) were quantified. AVR414 was prepared by plasmapheresis of healthy adults who had received a minimum of four subcutaneous injections of AVA. Mass values (mg/mL) for total IgG and IgG subclasses 1 to 4 were determined by radial immunodiffusion."

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