Medical Letter on the CDC and FDA

Heart Failure - U.S. FDA approves V-V timing in Medical Epic HF and Atlas+ HF CRT-Ds

Hereditary Angioedema - Final EDEMA1 results at presented at ACAAI meeting

Herpesvirus Outbreak - Owner likely spreads deadly herpesvirus to colony of captive common marmosets

Histoplasmosis - Functional T cells in primary immune response to histoplasmosis

Hyperlipidemia Therapy - Ezetimibe/simvastatin effective for treatment of hyperlipidemia

Hyperthyroidism - Iodine contaminants responsible for neonatal chemical hyperthyroidism in Nigeria

Immunology - Eosinophils secrete plasminogen activator inhibitor-2

Immunotherapy - Company receives FDA approval to begin sublingual-oral immunotherapy trial

Influenza - Next flu pandemic could kill 7 million people, according to WHO expert

Influenza Vaccine - TCR V beta repertoire directed against influenza CTL epitope reported

Information Technology - Compliance with U.S. FDA, Florida, California drug reporting timelines enabled

Insulin Pump - U.S. FDA alternate site clearance helps blood glucose meter users

Legal Issues - U.S. FDA comments further on complaint against Utah medical devices company

Leishmaniasis - Cutaneous leishmaniasis treated with lipid formulations of amphotericin B

Lyme Disease Diagnosis - C6 Lyme antibody test does not require Western blot for confirmation

Lyme Disease Vaccine - OspA protein of Borrelia burgdorferi vaccination results in neuropathy

Malaria -  Plasmodium falciparum polymorphisms analyzed from Brazilian Amazon region

Malaria - Individual malaria disease susceptibility/outbreak severity varies in Sudan

Malaria Vaccine - Membrane antigen and merozoite protein protect against P. chabaudi malaria

Measles Transmission - Airplane measles exposure offers lessons on disease contact response

Measles Vaccine - Impact of declining vaccination on subclinical measles infections reported

Medical Devices - Doctors perform states' first U.S. FDA-approved artificial disc replacements

Medical Devices - The current status of material used for depot delivery of drugs

Minamata Disease - Effects of methylmercury in neonatal brains determined

Multiple Sclerosis - U.S. FDA approves new drug to treat multiple sclerosis

Mutagenesis - Glycophorin A is potential biomarker for mutagenic effects of pesticides

Nicotine Addiction - Hopkins Institute for Global Tobacco Control receives recognition from PAHO/WHO

Norovirus - Detergent followed by bleach/detergent reduces Norovirus contamination

Nutrition - Older Americans not eating well

Obesity - Cardiovascular treatment drug used for smoking cessation also keeps weight off

Obesity Therapy - Recent advances in cannabinoids reviewed

Oncology - Biotech company announces commercial supply agreement for cancer treatment

Oncology - Biotech company announces initiation of Phase II trial for cancer treatment

Oncology - U.S. FDA accepts Onco-LIFE PMA supplement for filing

Overactive Bladder - U.S. FDA approves new medication

Pain Therapy - FDA issues approvable letter for Ralivia ER

Pharmaceutical Marketing - Pfizer halts Celebrex sales in Turkey in dispute over warning

Pneumocystis Carinii Pneumonia - Suspected pediatric PCP in resource-poor settings should be treated as emergency

Polio Epidemiology - Areas at increased risk for poliovirus circulation in Ecuador assessed

Premenstrual Dysphoric Disorder - Approvable letter granted for oral contraceptive containing drospirenone

Prescription Drugs - Doctors say statin drug should have been pulled sooner

Primary Care - Statewide emergency mental health preparedness plans compared

Prostate Cancer - Provenge data: Vaccine therapy for prostate cancer is shown to extend survival

Proteomics - Results change the paradigm for vitamin K-dependent protein carboxylation

Psoriasis - Clinical development of BCX-4208 for psoriasis initiated

Pulmonary Hypertension - Exacerbation of underlying pulmonary disease in pregnancy investigated

Pulmonary Hypertension - Exercise desaturation and pulmonary hemodynamics link unclear

Quality Assurance - Company's sera, media division registers as class I medical device manufacturer

Regulatory Issues - FDA called "defenseless" against bad drugs

Regulatory Issues - FDA tried to discredit whistleblower over drug safety claims

Respiratory Syncytial Virus - Palivizumab used to control RSV outbreak in neonatal intensive care unit

Rhabdomyolysis - Risk of muscle-damaging disorder low for most commonly prescribed statin drugs

Rheumatoid Arthritis Therapy - Compliance is viral for the success of TNF antagonist therapy

Rubella Vaccine - Immunization law revisions affect incidence of congenital rubella in Japan

SARS - Methods to inactivate SARS virus described

Sexual Health - Article: Controversial testosterone patch for women puts FDA on the hot seat

Sexual Violence - Grants awarded to end violence against women in conflict-affected areas

Sexual Violence - UNICEF: Impunity for rape and sexual violence in war must end immediately

Smallpox - Computer modeling helps identify new smallpox drug candidate

Smallpox Diagnosis - Rapid detection method for vaccinia virus developed

Thrombosis - First international standard for common genetic test approved by WHO

Toxoplasmosis Vaccine - Vaccination protects B cell-deficient mice against Toxoplasma gondii

Tuberculosis - Mathematical model predicts emergence of multidrug-resistant TB 'hot zones'

Tuberculosis - Small populations of fit MDRTB strains can out-compete low fitness strains

Urinary Tract Infection - Incidence of Salmonella-caused UTI has increased in elderly U.S. women

Vaccinia Virus Vaccine - Neutralizing antibody activities to vaccinia virus proteins are synergistic

Vancomycin Resistance - Two vancomycin-resistant E. faecium outbreaks in NICU caused by different clones

West Nile Virus - Economic impact of West Nile virus in Louisiana estimated

Wound Management - FDA clears V1 Wound Vacuum System for marketing, Medicare confirms coding

X-ray Imaging - Theory of X-ray imaging based on Wigner distributions developed

Yellow Fever Vaccine - Risk of fatal adverse events linked to 17DD yellow fever vaccine determined

Yersinia Pestis - Study shows evolution of virulent Yersinia pestis epidemic clone