Susan Hasty, Publisher
Table of Contents . . . December 26th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications
AIDS/HIV Transmission - Topical microbicides to prevent HIV-1 transmission compared
Mycobacteria - Taxonomy of Mycobacterium fortuitum determined
Neurology - FDA-approved neurologic devices for use in children reviewed
Regulations - Navigating the waters of U.S. Food and Drug Administration presented
Vagococcus - Vagococcus carniphilus isolated from ground beef
AIDS/HIV Pathogenesis - Leukocyte antigen alleles linked to viral load in HIV seroconverters
AIDS/HIV Vaccine - Disease-modifying HIV vaccines could increase epidemic severity
AIDS/HIV Vaccine - HIV immunization strategies involve adenovirus and poxvirus vaccine vectors
AIDS/HIV Vaccine - Increased HIV mucosal replication linked to mucosal cytokine activation
AIDS/HIV Vaccine - Method to predict impact of nonsterilizing vaccine against HIV developed
Acne - FDA announces enhancement to isotretinoin risk management program
Alzheimer Disease - Neurosciences center patents two potential Alzheimer treatments
Alzheimer Disease - U.S. FDA accepts sNDA to expand Namenda's indication
Angiology - Study investigated mechanisms of vitamin E suppression of aortic lesions
Anthrax Vaccine - Human immune response to U.K. anthrax vaccine characterized
Anti-Infectives - Yeast killer toxin-like antibodies possess therapeutic potential
Antibiotics - Antibiotic use database used for benchmarking and resistance research
Asthma - Investigational New Drug application for Aridol filed with the U.S. FDA
Asthma - Young volunteers sought for study to test if infant rash cream prevents asthma
Avian Influenza - H5N1 avian influenza A virus genome sequenced from Thailand poultry outbreak
Botulinum Toxin - Dosing and dilution of botulinum toxin reviewed
Brain Cancer - Daily topotecan blocks glioblastoma growth in animal models
Business & Finance - Medical technology company releases financial results
Business & Finance - Pharma company releases third quarter 2004 results
Cancer Epidemiology - Prostate leading newly diagnosed cancer among men; breast cancer leads for women
Cancer Research - Pharma company announces results from two clinical trials
Cancer Therapy - U.S. FDA approves new drug for the most common type of lung cancer
Chronic Fatigue Syndrome - Ampligen mentioned prominently at government meeting
Clinical Trials - Company suspends enrollment in phase 3 study of pathogen inactivation system
Collaborations - Genasense development agreements with Genta terminated
Colon Cancer Screening - More than 41 million Americans need colorectal cancer screening
Complementary and Alternative Medicine - Fenugreek extract found non-genotoxic
Contraception - U.S. FDA approves levonorgestrel, ethinyl estradiol for pregnancy prevention
Coronary Total Occlusions - Use of Safe-cross radiofrequency total occlusion crossing reported
Counterfeit Drugs - Drug tracking effort launched to support FDA battle against counterfeit drugs
Dengue Virus - Peridomestic mosquito adaptation mediates dengue emergence from progenitor DENV
Dermatitis - Company receives U.S. FDA nonapprovable letter for Extina
Diabetes Diagnosis - Method to determine acetone in human breath developed
Diabetic Neuropathy - Rural model to increase annual diabetic foot examinations presented
Diagnostics - Infectech engages Lake Erie Research Institute for FDA submissions
Diagnostics - PCR test differentiates between Staphylococcus aureus and S. intermedius
Diagnostics - U.S. FDA clears IQQA-Chest software for digital x-ray
Diet and Nutrition - Poor nutrition leads to stunting and wasting in Kenyan children
Drug Abuse - FDA clearance granted for new amphetamine test
Environmental Health - Toxic effects of trans-cinnamaldehyde characterized
Escherichia Coli - E. coli O157 cluster evaluation does not support epidemiologic association
Finance - Medical device company closes $4.3 million financing
Finance - Ohio organizations get federal funds for nonembryonic stem-cell research
Finance - Opthalmic medical devices company reports third quarter 2004 financial results
Finance - Pharmaceutical development company announces financial results
Finance - Research to reduce chemo's side effects receives state-federal dollars
Formaldehyde Exposure - No links found between formaldehyde exposure and leukemia
Gender & Health - Women and girls need access to AIDS therapies and protection from violence
Generic Drugs - Generic drugs developer gets U.S. FDA tentative approval for anticonvulsant drug
Geriatric Wellness - Report on aging and health in American finds unhealthy diets, lack of exercise
Global Health - Developing nations share stories of success
Global Health - Four million more health workers required to improve global health
Global Health - Important priorities for prevention and treatment of HIV/AIDS
Glycemic Control - Exendin-4 pharmacodynamics conducted
HIV Therapy - Interim results reported from second phase III study of tipranavir
HIV/AIDS Diagnosis - CDC updates status of HIV testing in U.S.
HIV/AIDS Disease Progression - Selenium status associated with increased HIV disease progression in pregnancy
HIV/AIDS Epidemiology - Rates of U.S. HIV/AIDS diagnoses are steady; racial disparities persist
HIV/AIDS Epidemiology - Ten U.N. agencies urge new focus on women and HIV in Latin America
HIV/AIDS Funding - $1.6 million grant will fund children's clinic in Tanzania
HIV/AIDS Funding - HHS awards $10.4 million to fight AIDS on 3 continents
HIV/AIDS Prevention - Counseling plus case management reduces HIV risk behaviors in IVDUs
HIV/AIDS Prevention - Inconsistent condom use related to abuse history and HIV serostatus
HIV/AIDS Prevention - Thousands rally to mark World AIDS Day in Bangladesh
HIV/AIDS Research - NIAID seeks applicants to lead revamped HIV/AIDS clinical trials networks
HIV/AIDS Risk - Asia marks World AIDS Day amid new warnings that women most at risk
HIV/AIDS Therapy - Two AIDS medicines back on WHO prequalification list
HIV/AIDS Transmission - Preventing infection among HIV+ men who have sex with men reviewed
HIV/AIDS Treatment - U.N. health agency reinstates two Indian AIDS drugs to approved list
HIV/AIDS Treatment - United Nations urges better help for women, girls infected with HIV
HIV/AIDS Trends - Government falls short of pledge to 'break the back' of AIDS
HIV/AIDS-Related Pneumocystis - Pneumocystis pneumonia infection is a continuing public health issue
Head Lice - State of head lice management and control reviewed
Healthcare & Politics - Washington State citizens' groups warn against Governor Locke's Rx Washington
Healthcare Benefits - HHS approves Maryland plan: Individuals with disabilities may direct own care
Healthcare Coverage - Disability income insurer announces settlement of multistate market conduct exam
Hemorrhagic Fever Virus - Evidence of segment reassortment in Crimean-Congo hemorrhagic fever virus
Hepatorenal Syndrome - U.S. FDA grants orphan drug status to I.V. Terlipressin
Immunology - Gen-Probe acquires rights to develop point-of-use platform for NAT instrument
Influenza - Americans flock to Canada for influenza vaccine
Influenza - Kriging analysis spots geographic/temporal trends in influenza epidemics
Influenza Vaccine - Efficacy of DNA influenza vaccine increased by Schiff base-forming drug
Information Technology - CliniComp to upgrade server platform for U.S. DoD military treatment facilities
Injury Prevention - Driving motorcycles safer but still far more dangerous than driving cars
Insomnia - New Drug Application submitted for insomnia treatment
Legal Issues - Company comments on patent infringement suit that seeks judicial declaration
Leishmaniasis Vaccine - Leishmania antigen and ODN protect against L. donovani infection
Lipid Studies - Current approaches to increasing HDL involve infusions of apoA-I
Listeria Monocytogenes - Pasteurization destroys Listeria monocytogenes in peanut and chocolate products
Liver Transplantation - Hepatopulmonary syndrome and portopulmonary hypertension reviewed
Lung Cancer - Biotech pharmaceutical firm gets U.S. FDA approval for lung cancer medicine
Lung Cancer - Tarceva approved for non-small cell lung cancer after failure of chemotherapy
Malaria - Susceptibility of Anopheles farauti to Plasmodium tested
Medical Device - Diagnostic devices company announced Model 100 completed safety testing
Medical Device - Healthcare services supports FDA policy on radio frequency identification
Medical Devices - EpiLift system for corrective vision surgery introduced
Medical Devices - FDA approves Xcelerant Delivery System with AneuRx AAA Stent Graft System
Medical Imaging - Kodak gets U.S. FDA approval for mammography system
Meningococcal C - Phase III program for Menjugate meningococcal C vaccine concluded
Mergers & Acquisitions - OEM medical device announces sale of AngioLink
Mosquito-Borne Disease - Commercial mosquito trap and gravid trap oviposition media evaluated
Multiple Sclerosis - Clinical trial of multiple sclerosis drug gets OK to proceed
Mycobacteria - Proteomic profiling of intact mycobacteria by MS conducted
Nicotine Addiction - Tobacco companies target U.S. immigrants
Nicotine Addiction - WHO tobacco treaty set to become law
Norovirus - Vaccine for food poisoning possible
Nosocomial Infections - Infection control measures rapidly controlled Norovirus hospital spread
Nutrition - Strict diet can help fight diseases like Alzheimer, E.U. scientists say
Obesity Epidemiology - CDC admits errors in obesity risk study
Obstetrics - Racial discrimination may contribute to premature births and low birthweight
Oral Contraceptive - Approvable letter for new oral contraceptive YAZ issued in United States
Outbreak Surveillance - Syndromic surveillance rapidly detects infectious disease outbreaks
Outbreak Surveillance - U.S. approach to outbreak detection uses five interacting health care systems
Overactive Bladder - U.S. FDA approves Vesicare for the treatment of overactive bladder
Overactive Bladder - U.S. FDA approves treatment for overactive bladder
Pain Medicine - Novartis withdraws application for E.U. approval of Prexige
Pain Medicine - Oxymorphone extended-release tablets approved by U.S. FDA
Pain Medicine - U.S. FDA approves protocol for oxymorphone extended-release tablets
Parasitology Vaccine - Veterinary parasitic vaccines reviewed
Patents - U.S. composition of matter patent for transported prodrug of gabapentin issued
Patents - U.S. patent issued for stabilized bioactive peptides
Pneumococcal Vaccine - Pneumococcal bacteremia in children in Barcelona reviewed
Pneumocystis Pneumonia Transmission - PCP transmitted from hospitalized HIV patients to renal transplant recipients
Prescription Drugs - Survey shows physicians have confidence in FDA approval process
Product Licensing - U.S. FDA approves depression drug citalopram hydrobromide
Prostate Cancer - New in vitro data on second-line chemotherapy for prostate cancer presented
Prostate Cancer - Phenoxodiol in patients with hormone-refractory prostate cancer results released
Prostate Cancer Therapy - Gonadotrophin-releasing hormone antagonist approved for prostate cancer
Pseudoporphyria - Pseudoporphyria resulting from voriconazole use reported
Quality Assurance - Health professionals group calls for probe into Iraqi healthcare system
Quality Assurance - Ontario leader says government on right track with doctors, healthcare
Rabies - Experimental rabies treatment sees success
Radioactive Poisoning - Agreement signed for Calcium-DTPA and Zinc-DTPA
Regulations - Agency finalizes new rules for "good tissue practice"
Regulatory Issues - FDA proposes draft guidance for new plant varieties intended for food use
Ricin Poisoning - UT Southwestern initiating trials in humans for ricin vaccine
SARS Prevention - Masks/handwashing effective but gowns/gloves not effective in SARS control
SARS Transmission - Main mode of SARS transmission through droplet spread and close/direct contacts
Salmonella Outbreak - Salmonella enteritidis outbreak associated with school-lunch dessert
Salmonella Outbreaks - S. enterica serotype typhimurium outbreak linked to raw milk consumption
Sepsis - Simple intervention nearly eliminates catheter-related bloodstream infections
Shellfish Poisoning - Paralytic shellfish poisoning outbreak caused by Gymnodinium catenatum
Smallpox Vaccine - Papular spongiotic dermatitis of smallpox vaccination reported
Smallpox Vaccine - Position statement on donor suitability after smallpox vaccination released
Smoking - Insulin-like growth factors decreased in men who smoke cigarettes
St. John's Wort - Stability of St. John's Wort in aqueous solutions determined
State Medicaid - HMS provides revenue collection for new Iowa Medicaid enterprise
Streptococcus - Streptococcus detection method helps prevent perinatal disease
Tobacco Use - World Health Organization says anti-tobacco treaty set to come into effect
Transplant Medicine - Biopharmaceuticals reports on progress in HepeX-C program
Transplant Medicine - Grant to help with detecting genes that contribute to transplant rejection
Uterine Fibroids - Surgery Without Incisions: New Frontiers for Radiology
Vaccinia Virus - Bacillus alcalophilus peptidoglycan inhibits vaccinia virus replication
West Nile Virus - CDC gravid trap attractants to West Nile virus vectors evaluated
West Nile Virus - High risk of meningoencephalitis in transplant recipients with WNV infection
Zoonoses - Discriminatory vaccination is modern strategy to control epizootic diseases
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