Medical Letter on the CDC and FDA

Influenza - Inappropriate antibiotic use for influenza increases drug resistance

Influenza A Pandemic - Genetic origins of 1918 flu pandemic different from 1957/1968 strains

Influenza Threat - World health officials warn of threat of global flu pandemic

Influenza Vaccines - Company to provide up to 4M emergency doses of flu vaccine to U.S. market

Influenza Vaccines - U.S. Health & Human Services Department, Ad Council launch flu vaccine campaign

Information Technology - Software systems developer receives $4 million Congressional grant

Information Technology - Three hospitals select company's document scanning and imaging solutions

Injury Prevention - Adults lack basic knowledge of pedestrian safety for children

Injury Prevention - Poison and firearms stored in open endanger visiting kids

Insomnia - U.S. FDA approves application for Lunesta brand eszopiclone

Legal Issues - Company announces litigation relating to announcement of Mucotrol's clearance

Legal Issues - Gambro Healthcare US reaches final agreement with U.S. Department of Justice

Legal Issues - Medical products company updates status of U.S. FDA lawsuit

Leishmaniasis Vaccine -  Leishmania major infection protects C3HEB/FEJ mice against L. amazonensis

Leprosy - Neural pathology in leprosy during treatment and surveillance reported

Leukemia - Additional data support clofarabine promise

Liver Cancer - Radiofrequency ablation improves hepatic colorectal metastases survival

Liver Failure - Liver damage from medicines, herbals at center of new study

Malaria Vaccine - Strain-specific humoral response to polymorphic malaria vaccine described

Medical Device - Diagnostic device maker completes fabrication of Model 100 Ambulatory ECG System

Menopause - Special Protocol Assessment granted by U.S. FDA for estroidal transdermal spray

Multiple Myeloma - Pivotal phase III trial for stem cell transplant drug to be initiated

Myiasis - Overview of status and future prospects of myiasis management released

Obesity Epidemic - Obesity is associated with poverty and low birth weight

Ophthalmology - Evolving guidelines for intravitreous injections outlined

Ophthalmology - Global pattern of blindness changes with success in tackling infectious disease

Organ Transplant - Chinese hospital claims success in digestive organs transplant

Osteoarthritis Therapy - Tramadol maker finalizes special protocol assessment with U.S. FDA

Osteoporosis - Pharma companies submitted NDA for injectable Boniva for osteoporsis

Otitis Media - Hemin utilization protein of Moraxella catarrhalis identified

Pain Management - Transdermally administered ibuprofen delivery system complete, NDA to be filed

Pain Medicine - IND filed for testing of extended release Ibuprofen

Pediatric Vaccine - MMR vaccination coverage needs improvement in Italy

Personnel - Stuart M. Krassner, ScD, elected to pharmaceutical company board of directors

Phenylketonuria - Phase III trial to be initiated for Phenoptin in 1Q of 2005

Plague Vaccine - Transcutaneous immunization with subunit antigens protects against plague

Polio Vaccine - Polio eradication in India reviewed

Pollution - New sensor could reduce emissions

Pollution - Stream vegetation can remove nitrogen in rainfall

Posterior Uveitis - U.S. FDA accepts NDA for Retisert implant for noninfectious posterior uveitis

Potable Water - Safe potable water provisions vary among hospitals caring for immunocompromised

Public Health - Youth smoking, drug use down again

Restless Leg Syndrome - Study tests effect of ropinirole HCl tablets on symptoms of primary RLS

Rheumatoid Arthritis - U.S. FDA accepts IND for antibody to treat active rheumatoid arthritis

Rickettsia Vaccine - Lysine methylations in Rickettsia prowazekii protein characterized

Rotavirus Vaccine - Rotavirus VP6 protein interacts with naive B cells via surface immunoglobulin

Rubella Vaccine - Role of the virology diagnosis laboratory in rubella surveillance outlined

SARS Vaccine - SARS-CoV S glycoprotein is promising vaccine candidate

SARS-Related Thrombosis - Increased incidence of thrombotic complications in SARS

Salmonella - Nosocomial S. enteriditis outbreak associated with lyophilized enteral nutrition

Salmonella Vaccine - Effect residual feed intake on Salmonella in hens investigated

Sexual and Reproductive Health - China defends 'one child' birth limits against U.S. criticism

Sexually Transmitted Disease - Management of sexually transmitted disease pandemic reviewed

Sexually Transmitted Disease - Vaginal microbicide compounds recognized as antigen by T lymphocytes

Skin Cancer - Diagnosis and treatment of basal cell and squamous cell carcinomas reviewed

Smallpox Vaccine - Hospital recruitment for smallpox pre-event vaccination program described

Smallpox Vaccine - Host response to smallpox in nonhuman primate model explored

Tetanus Vaccine - Immunogenicity of tetanus vaccine improved using promoter expressing FrgC

Thyroid Therapy - Levothyroxine sodium tablets bioequivalent to Synthroid, U.S. FDA says

Tissue Engineering - Tissue engineering company provides premarket approval status

Toxoplasmosis - IL-15-deficient mice develop protective immunity to Toxoplasma gondii

Trademarks - Two in 3 U.S. companies to use Madrid Protocol to streamline trademark process

Transfusion Technology - Care Fusion announces FDA 510k clearance for wBloodCare

Transplantation Medicine - Company receives FDA priority review designation for PULMINIQ NDA

Tuberculosis - Novel anti-tuberculosis agents with potent sterilizing activity are needed

Tuberculosis Vaccine - Novel in vitro system for evaluating antimycobacterial vaccines developed

Tuberculosis Vaccine - Positive tuberculin test may be caused by latent tuberculosis

Typhoid Fever Vaccine - Effect of dosage on immunogenicity of typhoid fever vaccine examined

Ulcerative Colitis - U.S. FDA grants REMICADE fast track designation for active ulcerative colitis

Urinary Albumin - Accumin urine albumin test receives expanded indications for use

Vaccine Development - Challenges of communicable diseases in complex emergencies reviewed

Vaccine Development - FLUVIRIN maker receives FDA warning letter

Violence - Issues related to defining and measuring violence against women outlined

Virology - IL-15 and IL-15R alpha mediates avidity maturation of memory CD8+ T cells

West Nile Virus - WNV VLPs are valuable tool to investigate tissue tropism in early infection

West Nile Virus - West Nile virus encephalitis an emerging disease in renal transplant recipients

World Health - United States pledges 20 million doses of smallpox vaccine to global stockpile

Yersinia Vaccine - LcrV synthesis required to confer immunity against Y. pseudotuberculosis