Medical Letter on the CDC and FDA

Bacteriology - Bacteria identified in juice using FT-near infrared spectroscopy

Diagnostics - Diagnosis of meningococcal disease with immunohistochemistry and PCR outlined

Environmental Health - Communication of information from toxic agents registry to public outlined

Food Safety -  Vibrio parahaemolyticus quantified in oysters using PCR

Radiation Therapy - Radiation doses in pediatric radiology discussed

Adverse Drug Events - Expert calls for less direct-to-consumer advertising

Adverse Drug Events - U.S. FDA orders review of pain drug studies

Adverse Drug Reaction - Detoxification of lithocholic acid has relevance to drug hepatotoxicity

Age-Related Macular Degeneration - Blindness association applauds U.S. FDA's decision to approve Macugen

Age-Related Macular Degeneration - U.S. FDA approves Macugen for treatment of neovascular wet AMD

Allergy Medicine - Interim analysis from ragweed allergy phase II/III trial announced

Alzheimer Disease - Company announces acceptance of DURIN IND application and clinical protocol

Alzheimer Disease - IND filed for approval of Alzheimer clinical trials

Amoebic Liver Abscess - Collagen-binding proteins protect hamsters from amoebic liver abscess

Amoebic Vaccine - Distribution of Entamoeba histolytica antibody response reported

Antibiotic Resistance - Study explores antibiotic misuse

Attention Deficit Hyperactivity Disorder - sNDA filed for new modafinil formulation for treatment of children and teens

Avian Influenza - Philosophy of fighting disease within European Union outlined

Bioterrorism - FDA recordkeeping rule to enhance the security of the U.S. food supply

Breast Cancer - Toremifene provides better profiles of lipid metabolism compared to tamoxifen

Burkholderia Cepacia -  Burkholderia cepacia complex isolated from hemodialysis unit outbreak

Business Update - Biopharma company prepared to select manufacturer for PHER-O2.

Business and Finance - U.S. FDA clearance for Macugen provides for milestone payment

Cancer Research - Cancer centers get $13.4 million for research

Cancer Therapy - Company expands oncology pipeline with product candidates from the NCI, PHS

Cancer Therapy - Company files IND application for anticancer compound XL880

Cancer Therapy - Riddelliine mutagenicity different in liver endothelial and parenchymal cells

Cancer Therapy - Small molecule CDC25 phosphatase inhibitors synthesized

Candidiasis - Non-albicans Candida spp. emerging as important pathogens in neonatal ICUs

Childhood Immunization - Vaccine contributions to health highlighted at expert meeting

Complementary and Alternative Medicine - L-carnitine and acetyl-L-carnitine promising for HIV-related complications

Compliance - HealthRamp announces Medicare e-prescribing rule-compliance status

Data Sharing - Researcher says U.S. FDA could broaden access to results of clinical drug trials

Dengue Virus - American/Asian dengue 2 virus genotype introduced into Yucatan State of Mexico

Dengue Virus - Genome from severe 2001 dengue-1 epidemic in French Polynesia characterized

Dengue Virus - Mosquitoes contribute to evolutionary conservation of dengue virus

Diagnostic Markers - Diagnostic markers and their ROC curves can be influenced by covariate variables

Diagnostics - Disseminated HPV-11 infection in patient with pemphigus vulgaris reported

Diagnostics - Rapid bioassay using bioconjugated nanoparticles detects single bacterial cell

Diagnostics - Real-time PCR quickly/accurately detects S. enterica and E. coli O157:H7

Disease Control - Effective animal disease control reviewed

Disease Control - WHO says coming days critical for control of disease in tsunami-hit countries

Disease Outbreaks - Experts fan out to prevent disease outbreaks in Sri Lanka

Domestic Violence - "Confident" living for people with special needs

Drug Addiction - IND application filed for CPP-109 to treat cocaine addiction

Drug Development - Company gets $12 million for Macroflux projects, requests U.S. FDA meeting

Drug Development - Indiplon NDA to be reformatted to access portions of electronic submission

Drug Development - Investigational new drug application submitted for SYR619

Drug Development - Pharma company to present MT 100 to FDA advisory committee

Drug Development - Pharmaceutical company submits IND for cancer drug, makes board appointment

Drug Development - Report on Cox-2 inhibitors indicates proof of safety difficult but crucial

Drug Development - Structural model assists in rational design of NRTIs with higher specificity

Drug Labeling - Strattera label wears new safety warning

Drug Resistance - Dissemination of E. coli producing CMY-11 due to cephamycin-resistant outbreaks

Echovirus - Echovirus 13 outbreak presented as viral meningitis in Lithuanian children

Environmental Health - Humans exposed to polybrominated diphenyl ethers through diet

Environmental Toxins - Better smoke-free policies needed in airports

Enzymology - Functional dissection of roles of budding yeast polo kinase Cdc5p explored

Epidemics - Probabilistic model demonstrates ability to forecast spread of epidemics

Epilepsy - Pharma company submits applications for antiepileptic and intravenous Keppra

Escherichia Coli - Enzyme-linked immunomagnetic chemiluminescence detects E. coli 0157:H7 in beef

Finance - Hawaii-based biopharma company awarded $15.5 million in NIH funding

Finance - Implantable tissue company files shelf registration statement

Finance - Pharmaceutical/neutraceutical company announces FY05 Q1 financial results

Generic Drugs - Approval granted for Demeclocycline Hydrochloride tablets

Generic Drugs - Pharma company receives final approval to market generic Accupril tablets

Generic Drugs - Pharma company recieves approval to market two generic drugs

Global Health - Vaccine program makes strides in increasing immunization coverage

HIV Therapy - Generic version of Videx EC antiretroviral agent approved by U.S. FDA

HIV/AIDS Epidemiology - HIV-1 sub-subtype A3 circulating in Senegal since 1988

HIV/AIDS Infection - Model of oral HIV exposure reveals extensive tonsil binding of HIV

HIV/AIDS Prevention - Scarcity of HIV/AIDS risk-reduction materials targeting older adults

HIV/AIDS Research - Novel system allows site/subunit-specific unnatural AA incorporation into HIV-RT

HIV/AIDS Screening - Company completes trials for two HIV rapid tests; nears PMA submission

HIV/AIDS Therapy - Enhancing ceramide levels inhibits HIV infection

HIV/AIDS Therapy - Invirase receives FDA marketing approval

HIV/AIDS Therapy - Novel tetrameric analog of indolicidin potent inhibitor of HIV-1 integrase

HIV/AIDS Therapy - Proinflammatory potential of microbicide candidates assessed

HIV/AIDS Therapy - U.S. FDA approves 500 mg HIV protease inhibitor to use with antiretrovirals

HIV/AIDS Therapy - Vaginal microbicide trials guided using biomarkers of inflammation

HIV/AIDS-Associated Infection - Widespread and invasive Trichophyton rubrum infection mimics KS in AIDS patient

HIV/AIDS-Related Infection - Intramedullary tuberculoma mimicked primary CNS lymphoma in AIDS patient

Hantavirus - HLA B8-DRB1*03 not associated with nephropathia epidemica severity in children

Head and Neck Cancer - New clinical data for Advexin shows promise

Hormone Replacement Therapy - U.S. FDA approves NDA for synthetic conjugated estrogen product