Oncology
Studies advance knowledge in oncology research
Published in Medical Letter on the CDC and FDA, January 30th, 2005
Study 1: Synthetic Grb2-SH2 domain binding antagonists staunch tumor and vessel growth.
According to recent research from the United States, "growth factor receptor bound protein 2 (Grb2) is an intracellular adaptor protein that participates in the signal transduction cascades of several angiogenic factors, including hepatocyte growth factor, basic fibroblast growth factor, and vascular endothelial growth factor."
"We described previously the potent blockade of hepatocyte growth factor-stimulated cell motility, matrix invasion, and epithelial...
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