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Sour Gas Exposure

GSTM1/T1 polymorphisms modulate blood changes associated with sour gas exposure

Published in Medical Letter on the CDC and FDA, February 6th, 2005

GSTM1/T1 polymorphisms modulate hematological changes associated with natural sour gas exposure.

"In order to find the effect of genetic polymorphisms of glutathione S-transferase M1 (GSTM1) and GSTT1 on hematological changes of individuals chronically exposed to natural sour gas, the present study was done.

"Study subjects (59 males, 55 females) were residents of contaminated areas of Masjid-i-Sulaiman (southwest of Iran). The GSTM1 and GSTT1 genotypes were determined using a polymerase chain reaction-based method," scientists in Iran report.

"The multiple linear regression method was applied. There is significant association...

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