Published in Medical Letter on the CDC and FDA, February 6th, 2005
"The present work demonstrates the presence of an impurity, 2,4,6-tribromoaniline (TBA), in the color additives D&C Red Nos. 21 and 21 lake (21L) and describes the determination of TBA in certified lots of D&C Red Nos. 21, 21L, and 22 (Eosin Y). A method was developed using solid-phase microextraction with [C-13(6)]TBA as an internal standard followed by gas chromatography-mass spectrometry analysis. Test portions from 23 lots of U.S.-certified color additives D&C Red...
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