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Coccidiosis Vaccine
In ovo subunit vaccine and cytokine genes protected against coccidiosis
February 20th, 2005
In ovo immunization with a recombinant subunit vaccine and cytokine genes elicited protective immunity against Eimeria acervulina. "A purified recombinant protein from Eimeria acervulina (3-1E) was used to vaccinate chickens in ovo against coccidiosis both alone and in combination with expression plasmids encoding the interleukin I (IL-1), IL-2, IL-6, IL-8, IL-15, IL-16, IL-17, IL-18, or gamma interferon (IFN-gamma) gene. When used alone, vaccination with 100 or 500 mcg of 3-1E resulted in significantly decreased oocyst shedding compared with that in nonvaccinated chickens. Simultaneous vaccination of the 3-1E protein with the IL-1, -15, -16, or -17 gene...
Source: Medical Letter on the CDC & FDA (2005-02-20)
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