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Medical Letter on the CDC & FDA

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Dengue Virus



Sustained dengue outbreak due to repeated introductions of different strains



February 20th, 2005

A sustained dengue outbreak is due to repeated introductions of different strains.

According to a study from Australia, "Outbreaks of dengue due to dengue virus type 1 (DENV-1) occurred almost simultaneously in 2001 in Myanmar and at multiple sites almost 10,000 km away in the Pacific.

"Phylogenetic analyses of the E protein genes of DENV-1 strains recovered from Asia and the Pacific revealed three major viral genotypes (1, 11, and 111) with distinct clades within each."

"The majority of strains from the Pacific and Myanmar, and a number of other Asian strains fell into genotype I. Genotype II comprised a smaller set of Asian and...


Source: Medical Letter on the CDC & FDA (2005-02-20)

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