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Tuberculosis

Recurrent tuberculosis in US/Canada mostly due to relapse with same strain

Published in Medical Letter on the CDC and FDA, March 20th, 2005

Recurrent tuberculosis in the U.S. and Canada is mostly due to relapses with the same strain of Mycobacterium tuberculosis.

"Recurrence of active tuberculosis after treatment can be due to relapse of infection with the same strain or reinfection with a new strain of Mycobacterium tuberculosis. The proportion of recurrent tuberculosis cases caused by reinfection has varied widely in previous studies.

"We evaluated cases of recurrent tuberculosis in two prospective clinical trials: a randomized study of two regimens for the last 4 months of treatment (n=1,075) and a study of a twice-weekly rifabutin-containing regimen for human...

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