Susan Hasty, Publisher
Table of Contents . . . March 27th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Medical Letter on the CDC and FDA | Other Publications
Gonorrhea - Genetic typing of porin protein of Neisseria gonorrhoeae reported
Influenza Vaccine - Medical practice expenses from influenza vaccinations estimated
Polio Vaccine - Spread of vaccine-derived poliovirus from a paralytic case reported
SARS Infection - SARS coronavirus replication in monocytes and macrophages described
Tobacco Use - Covariates of cigarette smoking in Hungarian children reported
Addiction Medicine - U.S. patent rights licensed for use of drug to treat nicotine dependence
Adenovirus - Sequence polymorphism in subspecies B1 human adenoviruses reported
Adverse Drug Reaction - U.S. FDA approves i.v. immune globulin for adverse reactions to smallpox vaccine
Aging - Life expectancy hits record high; gender gap narrows
Alcohol Use - College binge drinking associated with state drinking rates
Alcohol Use - Researchers identify networks of genes responding to alcohol in the brain
Malaria Vaccines - Studies advance knowledge in malaria vaccines research
Antiviral Therapy - Efficient synthesis of 5'-homoaristeromycin reported
Aspergillosis - EIA/qPCR used to diagnose invasive aspergillosis in high-risk patients
Asthma Risk Factors - Country of birth is risk factor for asthma among Mexican Americans
Avian Influenza - U.S. prepares to test bird flu vaccines
Bacterial Evolution - VNTRs appropriate evolutionary marker for studying bacterial transmission events
Benign Epidermal Pigmented Lesions - FDA approves pulsed dye lasers for benign epidermal pigmented lesions
Bioterrorism - Interpol lays out measures to combat bioterrorism
Breast Cancer - Positron emission mammography device detects small lesions
Breast Cancer - U.S. FDA clears MammoReport(Plus) for extended use
Breast Cancer - Urinary estrogen metabolite ratio may signal higher risk in Asian Americans
Breast Cancer Risk Factors - Risk factors differ by age, race among African American and white women
Buruli Ulcer - Dry-reagent PCR used to confirm Mycobacterium ulcerans in tropics
Business & Finance - Pharma company announces financial results
Business Update - Company announces implant of cryopreserved osteoarticular allograft
Cancer Diagnostics - Diagnostic products company files IND for biopsy product
Cancer Therapy - Study shows patients get more benefit than thought from early cancer treatment
Cancer Vaccines - TP-3 immunotoxins improve antitumor activity in mice with osteosarcoma
Clinical Trials - Eyetech uses InForm EDC for Macugen trials; Macugen launched in January
Congenital Heart Disease - ENU-induced mutations may yield insights into genetic basis of CHD
Congestive Heart Failure - U.S. FDA approval to begin trial for left ventricular assist system granted
Coronavirus - Recurrent feline coronavirus infection and role of cellular immunity reported
Cryptococcus Diagnostics - RT-PCR assay detects and quantitates Cryptococcus neoformans
Deerpox Virus - Genome of deerpox virus reported
Dermatology - Safety of ingredients used in cosmetics reviewed
Diagnostics - Two HIV rapid tests submitted to the U.S.FDA for PMA
Diet & Nutrition - School programs help reduce childhood obesity
Disease Management - Panel slams Japanese government for forced isolation of leprosy
Disease Prevention - An apple a day can help keep breast cancer away, suggests rat study
Disease Transmission - Risk of HSV-1 infection rises with oral sex
Drug Development - Pharmaceutical company files ANDA with U.S. FDA for opthalmic product
Drug Safety - Drug safety issues expected to slow companies' FDA product approval
Drug Safety - FDA wants power to write warning labels on drugs
Drug Safety - Warning issued on use of cholesterol drug Crestor by Asians
Electronic Medical Records - Poll: HIPAA notices have improved public's confidence
Emerging Disease - Plesiomonas shigelloides is emerging pathogen with unusual features
Enterotoxigenic Escherichia Coli - Phenotypes determined for ETEC associated with early childhood diarrhea
Environmental Health - IQ loss linked to mercury costs $8.7 billion
Environmental Health - Passive smoking kills 30 people a day in the U.K.
Escherichia Coli 0157 Diagnostics - IS1203 PCR rapidly genotypes Shiga toxin-producing Escherichia coli O157
Ethics - Publishers of second-hand smoke research had links to tobacco industry
Finance - COLD-EEZE manufacturer reports financial results
Finance - Cardio-focused medical devices company reports Q4, year ended December 31, 2004
Finance - Company attributes much of Q2's income drop to decline in ABELCET sales
Finance - Company focused on metabolic disorders reports Q4 and 2004 financial results
Finance - Company focused on protein deficiency treatments reports strong 2004 financials
Finance - MS drug's withdrawal triggers scrutiny of stock sales
Finance - Pharma company announces record financial results
Finance - Pharmaceutical company receives $750,000 equity investment
Finance - Science-based healthcare company reports Q4, full year 2004 financial results
Fitness - Urban green space linked to walking, cycling levels
Food-Borne Illness - Method of detecting Enterobacter sakazakii in infant formula developed
Fungal Therapy - Profile of an ideal antifungal presented
Gastroenterology - Treatment for upper GI bleeding, benign gastric ulcers released in U.S.
Gender Medicine - Thailand Ministry to campaign for breast-enlargement exercise
HIV/AIDS Coinfection - Schistosoma mansoni/HIV-1 coinfection leads to CD4 cell reduction
HIV/AIDS Diagnosis - Dual testing better for monitoring new cases of HIV
HIV/AIDS Epidemiology - HIV infection rate among blacks doubles
HIV/AIDS Epidemiology - New HIV strain has very deadly aspects
HIV/AIDS Infection - Influence of host genetic variation on susceptibility to HIV type 1 infection
HIV/AIDS Mental Health - Factors associated with victimization of African American female DUs identified
HIV/AIDS Prevention - Fear of test result and stigmatization are barriers to HIV testing in Bali
HIV/AIDS Prevention - HIV/AIDS risk perception predicted among low-income/urban/older adults
HIV/AIDS Prevention - High mobility among rural-urban migrants associated with increased sexual risk
HIV/AIDS Prevention - Rural Malawians publicly discuss strategies for HIV prevention
HIV/AIDS Prevention - Sexual compulsivity scores associated with risky sexual behavior frequency
HIV/AIDS Prevention - Youth with HIV take more risks after new meds introduced
HIV/AIDS Transmission - Older macaque infants are more susceptible than neonates to SHIV 89.6P
HIV/AIDS Vaccine - Antibody response elicited by trimeric HIV glycoproteins analyzed
HIV/AIDS Vaccine - HIV-1 virus-like particles are potent immune stimulators
HIV/AIDS Vaccine - Inactivated HIV antigen plus CpG ODN protects against infection
HIV/AIDS Vaccine - Modified HIV envelope proteins exhibit enhanced binding to antibodies
Haemophilus Vaccines - Studies describe new findings in haemophilus vaccines research
Health Promotion - Expert cautions against FDA approval of "race-based" pharmaceutical
Healthcare Disparity - Although disparities remain, improvements made in healthcare quality
Heart Failure - U.S. FDA approves candesartan cilexetil for the treatment of heart failure
Human Papillomavirus - Prevalence of human papillomavirus genotypes in women reported
Imaging - Technology company receives approval to expand use of ImageChecker D product
Infant Mortality - Call to action issued to address neonatal health issues
Infant Mortality - Individual solutions needed for poor countries to reduce neonatal death rates
Influenza - Vaccination programs for children in U.S., Canada based on little evidence
Influenza Vaccine - Norway to be supplied with special vaccines in event of influenza pandemic
Information Technology - GE Healthcare to supply U.S. government with pharmacy information system
Information Technology - Technology company releases donor management system for review
Information Technology - U.S. Department of Defense health system contracts for compliance software
Leishmaniasis - Promising visceral leishmaniasis treatments must translate into actual therapy
Leptospirosis - Percutaneous exposure results in laboratory-acquired leptospirosis
Licensing - Pharmaceutical firm acquires license to endothelinB agonists for chemo delivery
Listeriosis - Growth conditions affect thermal inactivation of Listeria
Lymphangioleiomyomatosis - High rate of abnormal BMD found in women with pulmonary disease
Malaria - Malaria morbidity in children increases as transmission intensity decreases
Malaria - Malaria still reduced in areas after withdrawal of deltamethrin spray
Malaria Diagnostics - Four plasmodium species detected in blood by real-time PCR
Malaria Therapy - Researchers provide details of new studies and findings in the area of malaria therapy
Malaria Vaccine - Baculovirus-based malaria vaccine shows promise in Senegalese village
Malaria Vaccine - Epitope mapping of malaria parasite inhibitory antibodies reported
Malaria Vaccine - Modified HRP-I peptide analogue protects against malaria
Malaria Vaccines - Reports add new data to malaria vaccines research
Marek's Disease Virus - Marek's disease virus genome copy number in chicken feathers quantified
Measles Vaccine - Measles genotype in Spain after measles elimination plan reported
Mergers & Acquisitions - Letter of intent signed to acquire parts of pHarlo Citrus Technology, 2 labs
Microbial Identification - Multispacer typing useful for strain genotyping during outbreaks/bioterrorism
Microbial Resistance - Beta-lactam susceptibilities evaluated against Enterobacteriaceae isolates
Microbial Resistance - In France, ESBL-producing S. enterica strains emerging in chickens & humans
Mosquito-Borne Disease - Aircraft is the main vessel for mosquito entry into New Zealand
Mycobacterial Infection - New mycobacaterial species found in sputum of patient with hemoptoic pneumonia
Mycobacterium Abscessus - Inability to type M. abscessus by PFGE assoc. with single clone of organism
Mycobacterium Xenopi Infection - Mycobacterium xenopi infection developed following heart transplantation
Myocardial Infarction - African Americans receive less aggressive heart attack treatment
Nosocomial Infections - U.S.FDA grants priorty status to drug for serious skin, soft tissue infections
Obstetric Fistula - Over 300 Nigerian women's obstetric injuries treated in first week of campaign
Obstetrics - Gestational night blindness seen in 18% of women attending Brazilian hospital
Obstetrics - U.S. FDA clear new fetal-health device
Orthopedics - Company gets FDA clearance for pivotal trial of Z-Lig device
Osteoporosis - Intervention results in significantly greater calcium intake among women
Pancreatic Cancer - U.S. FDA clears randomized portion of phase II TNFerade in pancreatic cancer
Parkinson Disease - European approval to market rasagiline 1 mg for Parkinson disease granted
Patents - Patent challenge of injection to treat migraine attacks in adults initiated
Patents - RNA-focused company granted 2 RNAi technology patents by U.K. Patent Office
Patents - Therapeutics company granted U.S. patent for developing allergy antibodies
Personnel - Richard C. Levin named CEO and president of natural personal products company
Philanthropy - U.N. health body welcomes Canadian gift
Pneumococcal Vaccine - Rapid multiplex assay for serotyping pneumococci developed
Pregnancy - Obese and tall women have increased incidence of fraternal twins
Probiotics - Use of probiotics reviewed
Prostate Cancer - Provenge/Avastin combo increases PSADT
Prostate Cancer - U.S. FDA approves new device for diagnosing and treating prostate cancer
Pseudomonas Aeruginosa - Pseudomonas aeruginosa is non-clonal but has an epidemic population
Rabies Vaccine - New rabies vaccine manufactured in India is safe and immunogenic
Regulatory Issues - FDA seeks drug-warning-label authority
SARS Coronavirus - Chronological evolution of Ab levels determined after SARS coronavirus infection
SARS Coronavirus - RT-PCR distinguishes SARS coronavirus from other respiratory tract infections
SARS Vaccine - Binding system restores interaction between SARS protein and receptor
SARS Vaccine - Intranasal immunization with inactivated SARS-CoV induces antibodies
SARS Vaccines - Recent findings illuminate research in SARS vaccines
Salmonella Vaccine - Type 1 fimbriae protects laying hens against Salmonella
Sexual Behavior - Contraception use not keeping up with conception rates in Latin America
Sexually Transmitted Diseases - Funding affects incidence of sexually transmitted diseases
Shigellosis Vaccine - Shigella flexneri vaccine strains characterized
Skin Cancer - Recent studies add new data to skin cancer research
Smallpox Vaccine - Smallpox vaccine does not protect macaques with AIDS from monkeypox
Smoking Cessation - "Truth" campaign driving youth smoking rates down
Smoking Cessation - Global tobacco treaty enters into force with 57 countries already committed
Smoking Cessation - Parents who quit smoking may influence their offspring to quit as young adults
Social Policy - Branding practices in rural India should be banned
Sociology - Child sex-trafficking study in Bosnia reveals misperceptions
Space Travel - Nanobacterial infections important during space travel
Spinal Cord Injury - U.S. FDA grants 510(k) clearance to market 2 fusion spine products in the U.S.
Spinal Cord Injury - U.S.FDA grants clearance of device to detect possible vertebral pedicle breach
Stem Cell Research - PTH/PTHrP signaling is major regulator of bone marrow ontogeny
Streptococcal Equi Diagnostics - Multiplex PCR differentiates closely related streptococcal species
Stroke - U.S. FDA accepts application for tool to aid in stroke assessment, diagnosis
Surgical Technology - Positive reaction to femoral puncture closure device, developer reports
Tick-Borne Virus - Tick-borne viruses in Europe are potential agents of bioterrorism
Tobacco Use - Treatment of tobacco dependence reviewed
Toxoplasmosis Vaccine - Toxoplasma gondii proteins protect against oral infection
Tuberculosis - M. tuberculosis lineage with low IS6110 copy numbers clonally expanded
Tuberculosis - Genotypic/phenotypic heterogeneity among M. tuberculosis isolates determined
Tuberculosis - Molecular genetic methods for mycobacterial research reviewed
Tuberculosis Vaccines - Cutaneous tuberculosis evoked by BGG vaccination in healthy baby
Tuberculosis Vaccines - Findings in tuberculosis vaccines provide new insights
Type 2 Diabetes - Diabetes prevention efforts worth every penny
Urea Cycle Disorder - Pharmaceutical company obtains FDA approval of treatment for urea cycle disorder
Vaccine Development - Biopharma initiates new Botulinum toxin therapeutic program
Vaccine Development - Sugar epitopes are potential disease transmission blocking targets
Vancomycin-Resistant Enterococcus - Esp/vancomycin resistance may contribute to clonal enterococcal dissemination
Vibrio Cholerae - Possible source of V. cholerae outbreak is effluent from ships or poachers
Virology - Studies add new findings to virology body of knowledge
Water-Borne Illness - Unsafe water, poor sanitation causes 4000 children to die each day
West Nile Virus - West Nile virus is an emerging arbovirus
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.