Lymphangioleiomyomatosis
High rate of abnormal BMD found in women with pulmonary disease
Published in Medical Letter on the CDC and FDA, March 27th, 2005
They recommend systemic assessment of BMD in these patients and starting them early on bisphosphonate, rather than antiestrogen, therapy to help reduce bone loss.
"Estrogen deficiency and pulmonary diseases are associated with BMD loss. Lymphangioleiomyomatosis (LAM), a disorder affecting women that is characterized by cystic lung lesions, is frequently treated with antiestrogen therapy, i.e., progesterone and/or oophorectomy," explained A.M. Taveirada-Silva and colleagues at the U.S. National Heart, Lung, and Blood...
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