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Tuberculosis

Genotypic/phenotypic heterogeneity among M. tuberculosis isolates determined

Published in Medical Letter on the CDC and FDA, March 27th, 2005

Genotypic/phenotypic heterogeneity among Mycobacterium tuberculosis isolates was determined.

According to recently published research from Belgium, "Although the heterogeneity of Mycobacterium tuberculosis populations and the existence of mixed infections are now generally accepted, systematic studies on their relative importance are rare.

"In the present study, 10 individual colonies of each M. tuberculosis isolate (primary isolate) from 97 tuberculosis patients in a primarily human immunodeficiency virus-negative population were screened for heterogeneity and detectable mixed infections by spoligotyping, IS6110-based...

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