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Gas chromatographic test to quantify bromopropane in urine developed

Published in Medical Letter on the CDC and FDA, April 10th, 2005

Scientists have developed of a headspace gas chromatographic test for the quantification of 1-and 2-bromopropane in human urine.

"1-Bromopropane (1-BP) is a commonly used industrial solvent, and 2-bromopropane (2-BP) is often found as an impurity component in industrial grade 1-BP. Both compounds are a health concern for exposed workers due to their chronic toxicity. Bromopropanes have been associated with neurological disorders in both animals and humans. Sample preparation consisted of diluting urine with water and fortification with 1-bromobutane (1-BB), which was used as an internal standard; then each sample was sealed in a headspace vial," scientists in the United...

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