Schistosomiasis Vaccine
Calpain found in penetration glands of Schistosoma japonicum cercariae
Published in Medical Letter on the CDC and FDA, April 10th, 2005
According to published research from Japan, "A monoclonal antibody was generated against the large subunit of Schistosoma japonicum calpain to study the localization and possible function of the molecule in vivo. Mice were immunized with recombinant S. japonicum calpain and polyclonal antisera and a monoclonal antibody specific to schistosome calpain was obtained."
"In immunohistochemistry, a monoclonal antibody against S. japonicum calpain, KG-2E11, bound weakly to calpain expressed at the surface of adult worm tegument,...
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