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Asthma

Interleukin-5 controls UGRP-1 during allergic airway inflammation

Published in Medical Letter on the CDC and FDA, April 10th, 2005

Interleukin-5 controls UGRP-1 during allergic airway inflammation.

"Airway inflammation is thought to play a major role in the pathogenesis of bronchial asthma. The precise role of individual inflammatory cells, mediator and asthma related genes in allergic lung diseases is not completely understood. The uteroglobin-related protein (UGRP) 1 was proposed to be an asthma candidate gene and play a role in regulating lung inflammation, however, its precise function in the airways remains obscure," investigators in the United States report.

"In this investigation, we used a mouse model of allergic airway inflammation to establish a relationship between...

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