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Smallpox Vaccine

Severe headaches common after smallpox vaccination

Published in Medical Letter on the CDC and FDA, April 10th, 2005

Severe headaches are common after smallpox vaccination.

According to published research from the United States, "Headaches are common following smallpox vaccination; the re-introduction of civilian vaccination necessitates better understanding of the clinical features and outcome of post-vaccination headache. We identified patients reporting headache following vaccination from among those reported to the U.S. Vaccine Adverse Events Reporting System to characterize demographic and clinical features. One-hundred and eight reports were obtained from among 627 smallpox vaccine-related reports, including 15 hospitalized persons."

"None had neurologic...

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