Medical Letter on the CDC and FDA

Global Health - High rates of death and malnutrition seen among displaced populations

HIV-2 Drug Mutation - Polymorphisms specific to HIV-2 identified in untreated patients

HIV/AIDS Epidemiology - Low CCR5Delta32 frequency related to higher susceptibility to HIV-1 infection

HIV/AIDS Mortality - Net survival for HIV-infected children is 67% at 1 year and 39% at 5 years

HIV/AIDS Mortality - Parental mortality from AIDS decreases primary school attendance in Tanzania

HIV/AIDS Prevention - Discrete-event simulation evaluates vertical transmission prevention strategies

HIV/AIDS Research - Advances in laboratory testing for HIV used to follow disease process

HIV/AIDS Therapy - Research add new data to HIV/AIDS therapy body of knowledge

HIV/AIDS Transmission - Sexual prejudice significant predictor of false beliefs about HIV transmission

HIV/AIDS Vaccines - Reports describe recent advances in HIV/AIDS vaccines research

HIV/AIDS-Related Diabetes - Apparent type 1 diabetes resolves in AIDS patient with CMV coinfection

HIV/AIDS-Related Orthopedics - Sepsis not seen during 1-year follow-up of orthopedic implants in HIV infection

HIV/AIDS-Related Tumor - Cardiac tumor was initial manifestation of AIDS

Health Promotion - Global tobacco surveillance system (GTSS) yields comprehensive and useful data

Healthcare Disparity - Minorities, poor, uneducated bear burden of differences in healthcare

Influenza Vaccine - Chinese government grants new drug certificate for split flu vaccine

Information Technology - Medical center adopts scannable identification chip for emergency department

Intestinal Tuberculosis - Imaging findings described for intestinal tuberculosis

Klebsiella Pneumoniae - ESBL-positive K. pneunmoniae clones cause sustained epidemic outbreaks

Legal Issues - Denial of motion to prevent launch of generic forms of dental drug recommended

Malaria Vaccines - New data illuminates research in malaria vaccines

Mastocytosis - Open-label study of ZYFLO begins

Measles - Scientists examine D7, a new measles virus genotype

Medical Devices - Application filed with U.S. FDA for approval to use spine manipulation device

Meningococcal Vaccine - Company seeks U.S. FDA approval to broaden age group for meningococcal vaccine

Menopause - NIH panel calls for "demedicalization" of menopause

Mergers & Acquisitions - Biotechnology company closes merger with Panacos Pharmaceuticals

Microbial Forensics - Identifying and attributing pathogens to source next great forensic challenge

Multiple Myeloma - PML mediates IFN-alpha-induced myeloma apoptosis by regulating TRAIL induction

Nasopharyngeal Cancer - U.S. FDA grants 510(k) clearance for applicator for brachytherapy treatments

Nosocomial Infection - VUMC researchers find drug-resistant bacteria MRSA a growing threat

Oral Health - Genetic shifts in injured oral mucosa define potential therapeutic targets

Osteoporosis - Recent findings in osteoporosis described

Otology - Researchers track trends in cochlear implant complications

Pain Management - U.S. FDA approves rechargeable implantable pulse generator

Patents - Company issued patent for human factor 5A genes, 2 others for agricultural use

Patents - Pharmaceutical company agrees to settle patent interference action

Patents - Technologies company granted European patent in chronic heart failure

Personnel - David A. Saperstein named to opthalmology company's scientific advisory board

Personnel - Developer of stem cell expansion products announces new president and CEO

Personnel - Rudi E. Moerck hired as consultant by cancer-focused pharmaceuticals company

Pertussis - Medical group comments on U.S. FDA recommendation for pertussis vaccine

Plague - Researchers distinguish bioterrorism and naturally occurring plague infections

Pneumonia - Invasive pneumonia, drug resistance lower after childhood vaccine introduced

Postpartum Depression - Pituitary-adrenal axis of women with PPD is more sensitive to gonadal steroids

Public Health - Public policy should address the social factors behind ill health

Public Health - Rural America vulnerable to bioterrorism and natural disaster threats

SARS - New studies suggest airborne SARS transmission is possible

SARS - Researchers provide details of new studies and findings in the area of SARS

Salmonella Infection -  Salmonella variation responsible for differences within herd dynamics

Schistosomiasis - Reports add new data to schistosomiasis research

Sexual & Reproductive Health - HIV and ID doctors oppose ideologically driven STI prevention policies

Smallpox - Smallpox drug in preclinical development to study primate efficacy, human safety

Smallpox Vaccines - Researchers describe findings in smallpox vaccines studies

Stem Cell Research - Low-dose total body irradiation causes clonal fluctuation of stem cells

Stroke - Neurobiological technology co. reports on end of phase II meeting with U.S. FDA

Tobacco Use - Tobacco industry cast doubt on link between smoking and p53 mutations

Tuberculosis -  Mycobacterium tuberculosis proteasomal ATPase homologue characterized

Tuberculosis - Magnetic resonance spectroscopy diagnoses cerebral TB from neurocysticercosis

Tuberculosis - Phagosomal elemental concentration change by M. tuberculosis Mramp described

Tuberculosis - Regulatory sequence recognized by M. tuberculosis MprA identified

Tuberculosis - Two-step approach is optimal for genotyping M. tuberculosis isolates

Vaccine Development - Dutch biotech, VRC extend Ebola vaccine agreement

Vaccine Development - FDA advisory panel recommends licensure of ADACEL vaccine

West Nile Virus - Public health interventions limited in ability to deal with multiple epidemics