Malaria

Origin of Plasmodium vivax as human malaria parasite reviewed

Published in Medical Letter on the CDC and FDA, May 8th, 2005

Scientists review the origin of Plasmodium vivax as a human malaria parasite in a recent issue of the Proceedings of the National Academy of Sciences of the United States of America.

"The high prevalence of Duffy negativity (lack of the Duffy blood group antigen) among human populations in sub-Saharan Africa has been used to argue that Plasmodium vivax originated on that continent. Here, we investigate the phylogenetic relationships among 10 species of Plasmodium that infect primates by using three genes, two nuclear (beta-tubulin and cell division cycle 2), and a gene from the plastid genome (the elongation factor Tu). We find compelling...

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Source: Medical Letter on the CDC and FDA (2005-05-08)

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