Medical Letter on the CDC and FDA

Home Healthcare - FDA clears new Health Buddy appliance

Hormone Replacement Therapy - Women confused about trends in hormone therapy treatments, online survey shows

Immunology - Antigen receptor requires caspase-8 for NF-kappa B activation

Influenza Vaccine - Economic evaluation of influenza vaccination in elderly conducted

Influenza Vaccine - Efficacy of influenza vaccine among U.S. military trainees reported

Influenza Vaccine - Inactivated influenza vaccine prevents influenza in diabetic mice

Injury Prevention - Alcohol-impaired driving on the increase

Injury Prevention - Community-based campaigns increase helmet use by child cyclists

Injury Prevention - Football is a pain in the neck

Insomnia - FDA issues approvable letter for AMBIEN CR for the treatment of insomnia

Insulin Resistance - Studies describe new findings in insulin resistance research

Legal Issues - Court rules in favor of ephedra

Leishmaniasis - Fate of CD4+ T cells during Leishmania donovani infection examined

Leishmaniasis - LdARL-1 His-tagged recombinant protein purified

Leishmaniasis Vaccines - New research in the area of leishmaniasis vaccines detailed

Lipoproteins - Capture assays for modifications of low-density lipoprotein developed

Lung Cancer - Study evaluates stability of decline in lung cancer incidence among U.S. women

Malaria - Antioxidants reduce endothelial cell apoptosis in malaria

Malaria Epidemic - Link between climate variability and malaria epidemics still unproven

Malaria Genomics and Genetics - Mutations linked to chloroquine resistance lower Plasmodium fitness

Malaria Transmission - Entomological features of malaria transmission in Manhica reported

Malaria Vaccines - New data illuminates research in malaria vaccines

Marketing - Agreement reached to Promote Xenical for diabetes prevention

Medical Devices - Defibrillator company upgrades cardiac devices with V-V timing programmability

Medical Devices - Implant maker comments on U.S. FDA panel's recommendations

Medical Devices - U.S. FDA grants two 510K clearances for electrophysiology catheters

Melanoma Vaccine - NY-ESO-1 antigen epitopes not beneficial in metastatic melanoma

Mental Health - Living arrangements affect well-being of mothers with mental illness

Mergers & Acquisitions - Prescription products company and Osmotics Pharma, Inc., announce merger

Metabolic Syndrome - Prevalence of metabolic syndrome increasing in Chinese population

Multiple Myeloma - REVLIMID clinical results from phase III trial announced

Multiple Myeloma - Results of study of bortezomib injection to treat multiple myeloma reported

Myelodysplastic Syndromes - REVLIMID new drug application submitted to U.S. FDA for review

Neisseria - Epidemiology of nasopharyngeal carriage of Neisseria discussed

Neurotoxicology - Systems biology approach applied to developmental neurotoxicology

Nosocomial Infections -  L. pneumophila persist in water supply regardless of disinfection procedures

Obesity Epidemiology - Being obese, underweight, associated with increased risk of death

Obstetrics - Genetic polymorphisms associate with cerebral palsy risk in preterm infants

Ophthalmology - Platelet-derived growth factor D inhibitors could treat ocular disorders

Opportunistic Infections - Guide for treating opportunistic infections in HIV+ people released

Ovarian Cancer - Company granted FDA orphan drug status for Panzem (2ME2) in ovarian cancer

Pain Management - Agency announces series of changes to the class of marketed NSAIDs

Pain Management - Rechargeable neurostimulation system for chronic pain approved by U.S. FDA

Pain Management - U.S. FDA issues approvable letter to market sugar-free Actiq

Parasitology - Lung-migrating digenean parasites investigated

Pediatric Vaccines - Household economics predict childhood immunization in Caribbean

Pediatric Vaccines - Immunization information database described

Personnel - Gordon Snyder named VP of sales at device company

Personnel - Pharma company appoints member to board

Pertussis - RisA activates vrg6 promoter of Bordetella pertussis

Poxvirus - Poxvirus tropism reviewed

Preventive Medicine - Managed care plans do not reduce racial disparities in preventive care

Preventive Medicine - NCI taps Endeca to power search of comprehensive collection of cancer info

Prion Disease - Copper binding to prion octarepeat peptides described

Psittacosis Outbreaks - Psittacosis outbreak may be linked to wild birds

Psoriasis - Pharma company plans to commence phase II trials for Xantryl

Recombinant Technology - Mut phenotype allows easier protein production in Pichia cultures

Regulatory Issues - Patients' lives at risk from substandard drugs, say heart specialists

Rotavirus Genomics and Genetics - Rotavirus strains in Danish population characterized

SARS Coronavirus - SARSCoV mutation rates correlate with geographic epidemic characteristics

SARS Coronavirus - Safe & sensitive Spike protein-based IFA detects antibody responses to SARS-CoV

SARS Vaccines - New findings in SARS vaccines described

Smallpox Vaccine - Consequences of smallpox attack re-examined

Stem Cell Differentiation - Complex extracellular matrices promote tissue-specific stem cell differentiation

Stroke - FDA approves HYZAAR to help prevent stroke in those with hypertension and LVH

Surgical Technology - FDA approves cranial dural sealant

Tetanus Vaccine - Tetanus protection in elderly people in Czech Republic examined

Tobacco Use - Diet and tobacco exposure to acrylamide influence hemoglobin AA-adduct levels

Toxicology - Plastics compounds act as environmental estrogens, alter breast gene expression

Toxicology - Subchronic toxicity of elemental Nano-Se in Sprague-Dawley rats studied

Toxicology - UVA light-formation photodecomposes retinyl palmitate

Transfusion Medicine - Prestorage leucodepletion reduces transfusion reactions events

Transplant Medicine - Pediatric immune systems study to improve young transplant patients' treatments

Tuberculosis - Assays to determine vaccinated from M. bovis infected cattle improved

Tuberculosis Diagnosis - Culture more sensitive than PCR for extrapulmonary tuberculosis diagnosis

Tuberculosis Drug Development -  Quinchamalium majus constituents have potential antitubercular activity

Tuberculosis Vaccine - Prescreening program tested a wide range of tuberculosis vaccines

Tuberculosis Verrucosa Cutis - Diagnostic criteria for tuberculosis verrucosa cutis discussed

Uveitis - Antigen 4 blockade in patients with metastatic melanoma causes uveitis

Vaccine Development - License application submitted for investigational vaccine for rotavirus

Vaccine Development - PCR-based assay of DNA impurities in protein preparations developed

Vaccine Efficacy - Immunizations benefitting college students reviewed

Venous Ulcers - Information for U.S. FDA premarket approval for venous ulcer treatment received

West Nile Virus - NIAID begins clinical trial of West Nile virus vaccine

West Nile Virus - Studies describe new findings in west nile virus research

Yersinia - Invasin triggers Rac1-mediated signals enabling Yersinia internalization

Yersinia - LAT/SLP-76 molecules targeted by Yersinia to inhibit T cell activation