SARS Coronavirus
Safe & sensitive Spike protein-based IFA detects antibody responses to SARS-CoV
Published in Medical Letter on the CDC and FDA, May 15th, 2005
"Previously, we have identified a truncated antigenic fragment named protein C [441 to 700 amino acids (a.a.)] as the immunodominant fragment of Spike (S) protein of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV). We have now successfully expressed protein C using the baculovirus system in S. frugiperda (Sf-9) cells," scientists in Singapore report.
"This recombinant baculovirus expressing protein C was first characterized using five SARS convalescent human sera and five normal human sera. The results showed that protein C is ail authentic antigen...
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