Rotavirus Vaccine
Infection of pigtailed macaques with simian rotavirus infection
Published in Medical Letter on the CDC and FDA, May 15th, 2005
"Experimental rotavirus infection was investigated in pigtailed macaques to study the infectivity, immunity, and pathogenesis of rotavirus. A challenge virus, YK-1, was administered intragastrically to four seronegative macaques (age 11-16 months). Although none of the monkeys developed diarrhea, an active infection occurred with high titers of rotavirus antigen detected in stools 2 to 10 days after challenge. These animals developed rotavirus-specific antibody responses similar to those seen following primary exposure to rotavirus," investigators in the United States...
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