Published in Medical Letter on the CDC and FDA, May 15th, 2005
"Experimental rotavirus infection was investigated in pigtailed macaques to study the infectivity, immunity, and pathogenesis of rotavirus. A challenge virus, YK-1, was administered intragastrically to four seronegative macaques (age 11-16 months). Although none of the monkeys developed diarrhea, an active infection occurred with high titers of rotavirus antigen detected in stools 2 to 10 days after challenge. These animals developed rotavirus-specific antibody responses similar to those seen following primary exposure to rotavirus," investigators in the United States...
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