Adverse Drug Reaction

Use of data-mining algorithms to detect adverse drug reactions reviewed

Published in Medical Letter on the CDC and FDA, May 15th, 2005

Scientists evaluate the potential utility of data-mining algorithms for early detection of potentially fatal/disabling adverse drug reactions in a recent issue of the Journal of Clinical Pharmacology.

According to recent research from the United States, "The objective of this study was to apply two data-mining algorithms to a drug safety database to determine if these methods would have flagged potentially fatal/disabling adverse drug reactions that triggered black box warnings/drug withdrawals in advance of initial identification via 'traditional' methods. Relevant drug-event combinations were identified from a journal publication. Data-mining algorithms using...

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Source: Medical Letter on the CDC and FDA (2005-05-15)

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