HIV/AIDS Vaccines
Reports describe recent advances in HIV/AIDS vaccines research
Published in Medical Letter on the CDC and FDA, May 22nd, 2005
Study 1: Vaccine-elicited antibodies mediate antibody-dependent cellular cytotoxicity correlated with significantly reduced acute viremia in rhesus macaques challenged with SIVmac251 .
According to a study from the United States, "Effector cells armed with antibodies can eliminate virus-infected target cells by antibody-dependent cellular cytotoxicity (ADCC), an immune mechanism that has been largely overlooked in HIV vaccine development. Here, we show that a prime/boost AIDS vaccine approach elicits potent ADCC activity correlating with protection against SIV in...
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