Viral Clearance
Re-use of ion chromatography media does not decrease virus removal
Published in Medical Letter on the CDC and FDA, May 29th, 2005
"We evaluated viral clearance in multiply-cycled anion-exchange media run in flow-through mode. We found that anion-exchange columns do not lose viral clearance capacity after extensive re-use, if they are cleaned with recommended buffers that do not chemically degrade the media. In contrast, anion-exchange (AEX) columns that are not cleaned or are cleaned with buffers that chemically degrade the media lost viral clearance capacity after extended use," investigators in the United States report.
"In these...
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