Lipopolysaccharide
LPS-specific peptides screened using epoxy beads
Published in Medical Letter on the CDC and FDA, June 5th, 2005
"The selection of identical or highly homologous peptides from phage display combinatorial peptide libraries has been unsuccessful in biopanning experiments using microtiter plates. In the present study, by biopanning on LPS-conjugated epoxy beads, we repeatedly enriched clones encoding AWLPWAK and NLQEFLF. These peptides were found to interact with the polysaccharide moiety of LPS, which is highly variable among Gram-negative bacterial species," scientists in South Korea report.
"In addition, phages encoding these peptides...
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