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HIV/AIDS Vertical Transmission

CD4 count and HIV RNA are independent risk factors for mortality after delivery

Published in Medical Letter on the CDC and FDA, June 19th, 2005

CD4 count and HIV RNA are independent risk factors for mortality after delivery.

"The objective of this study was to analyze the mortality during the first 24 months after delivery in relation to CD4 T-lymphocyte levels and viral load at enrollment (36 weeks of gestation) in a cohort of HIV-1-seropositive breast-feeding women at the Dar es Salaam site of the multicenter Petra trial (a mother-to-child HIV-1 transmission intervention trial using antiretroviral therapy).

"Antiretroviral treatment was not available in this setting apart from the short treatment given within the trial around delivery to prevent mother-to-child transmission of HIV...

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