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Anti-infectives

Tribendimidine is promising, broad-spectrum anti-helmintic agent

Published in Medical Letter on the CDC and FDA, June 26th, 2005

Tribendimidine is a promising, safe, and broad-spectrum anti-helmintic agent from China.

"We review, for the first time, a 20-year Chinese story of research and development pertaining to tribendimidine, a promising anti-helmintic agent that is safe and exhibits a broad spectrum of activity. Tribendimidine was first synthesized at the National Institute of Parasitic Diseases in Shanghai in the mid 1980s. In laboratory studies, tribendimidine showed high efficacy against Nippostrongylus braziliensis in rats, Necator americanus in hamsters, Ancylostoma caninum and Toxocara canis in dogs, and Syphacia mesocriceti in mice," investigators in...

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