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Vitamin C modulates T cells only during T cell activation

Published in Medical Letter on the CDC and FDA, June 26th, 2005

Mega-dose vitamin C modulates T cell functions in BALB/c mice only when administered during T cell activation.

According to recent research from South Korea, "Previously we reported that a mega-dose of Vitamin C enhanced the initial stage of delayed-type hypersensitivity reaction in BALB/c mice. In this study its effects were further evaluated as follows. Mice were administered vitamin C intraperitoneally at 0.625 mg/day or at 5 mg/day for variable days before, during, or after being sensitized with DNFB. T cells were isolated in each group and examined."

"When stimulated antigen-specifically or non-specifically in vitro, mice showed elevated...

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