Drug Resistance

Nevirapine resistance may be higher than previously thought

Published in Medical Letter on the CDC and FDA, June 26th, 2005

The incidence of drug resistance associated with single-dose nevirapine, a drug used to prevent mother-to-child transmission of HIV-1, may be substantially higher than previously thought and of particular risk for those infected with HIV-1 subtype C.

This is according to three new studies published in the July 1, 2005, issue of the Journal of Infectious Diseases, now available online.

A single dose of nevirapine given to an HIV infected pregnant woman during delivery, and another given to her newborn, can cut the rate of mother-to-child HIV transmission in half. The relative simplicity and affordability of single-dose nevirapine have made it...

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Source: Medical Letter on the CDC and FDA (2005-06-26)

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