Tuberculosis Diagnostics
Pulmonary tuberculosis rapidly diagnosed via mass spectrometry method
Published in Medical Letter on the CDC and FDA, July 3rd, 2005
According to a recently published study from Belgium, "A fast method for detection of tuberculostearic acid (TBSA) in sputum samples is described.
"The samples, obtained from patients with known or suspected pulmonary tuberculosis, were decontaminated and concentrated before being analyzed by stir bar sorptive extraction-thermal desorption-gas chromatography-mass spectrometry (SBSE-TD-GC-MS)."
"Prior to extraction, the mycobacterial lipids were hydrolyzed and then derivatized with ethyl chloroformate to increase the sorption of the compounds by the...
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