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Susan Hasty, Publisher Table of Contents . . . July 24th, 2005 Non-Subscriber - Summaries Only Related Areas: Other Issues in Medical Letter on the CDC & FDA | Other Publications
Environmental Health - National exposure measurements to protect public health releasedHIV/AIDS Therapy - Natural resistance of HIV type 2 to zidovudine describedHuman Papillomavirus - Gene expression profile of cervical cells harboring HPV-16 reportedListeriosis - Outbreak of listeriosis in U.S. traced to contaminated hot dogsPap Test - Physician recommendation improves likelihood of Pap testingAcinetobacter Baumannii - Imipenem-resistant A. baumannii outbreak produced OXA-23 beta-lactamaseAllergy & Immunology - Formoterol fumarate inhalation powder for asthma and COPD approved in GermanyAllergy Medicine - Minority children not less likely to be diagnosed with asthmaAllergy Risk Factors - Routine immunizations do not reduce hay fever riskAmyotrophic Lateral Sclerosis - Phase II trial for ALS expected to begin after second quarterAnopheles - Deforestation facilitates survival of immature stage of Anopheles gambiae Obstetrics - Researchers provide details of new studies and findings in the area of obstetricsAntimicrobial Drug Adherence - Pharmionics measures patient adherence to prescribed antimicrobial drug regimensAsbestos - Computed tomography useful in detecting asbestos-related abnormalitiesAspergillosis - Scoring system developed to help predict risk of invasive aspergillosisAtrial Fibrillation - Dr. Andrea Natale files IDE for use of the linear ablation technologyAvian Influenza - Researchers describe findings in avian influenza studiesBacterial Vaginosis - TNF-alpha secretion/TLR4 mRNA expression stimulated in bacterial vaginosisBiomedical Engineering - U.S. NIH selects Vanderbilt University for new molecular screening centerBlood Safety - Pathogen inactivation proactively protects the blood supplyBrain Cancer - No significant increase in glioma risk seen in women exposed to farm pesticidesBrain Injury - Characteristics of traumatic brain injury in elderly people describedBreast Cancer - Researchers seek quicker, less invasive cancer detectionBreast Cancer - U.S. FDA: Second Look Digital can be packaged with MAMMOMAT NovationDRBreast Cancer Screening - Women want to participate in decision on first mammogramBurkholderia Pseudomallei - Schema developed for laboratory identification of Burkholderia pseudomallei Business & Finance - Cancer-, hepatitis-focused company affirms clinical progress, notes milestonesBusiness Update - Company gets orphan drug designation for PrestaraBusiness Update - DARPA to sponsor evaluation of CX717 in a new study in shift workBusiness Update - FDA approves Immedia PT SystemBusiness Update - Radiofrequency ablation company completes manufacturing transferBusiness Update - U.S. FDA clears ICG device with 12-lead ECGCancer Prevention - Selenium levels relate inversely to liver cancer occurrenceCancer Research - Pharma company presents broad antiviral potential of Tarvacin at conferenceCancer Therapy - Influence of type 2 diabetes on cancer treatment and outcome reportedCancer Therapy - U.S. FDA grants fast track status for Fodosine in refractory T-cell leukemiaCardiology - Transmyocardial revascularization and gene therapy fight myocardial dysfunctionCardiovascular Disease - Rimonabant accepted for filing by the FDACervical Dystonia - Trial shows Myobloc clinically equivalent to Botox in cervical dystoniaChemotherapy - Tentative FDA approval received for Ondanestron HydrochlorideChickenpox Vaccine - Oka/GSK attenuated varicella vaccine prevents chickenpoxChildhood Cancer - Public health partnerships of childhood cancer studies examinedChlamydia Trachomatis - Higher vaginal pH associated with Chlamydia trachomatis infection in womenChlamydiosis - Azithromycin should be effective against IFN-gamma-induced persistent infectionClinical Trials - Bioscience company expands development program for EGFR inhibitor nimotuzumabCoccidioidomycosis Vaccine - Immune response of vaccinated mice to Coccidioides investigatedColorectal Cancer - Gene methylation may play an important role in adenoma recurrenceCosmetics - OTC progesterone cream results in significant drug exposureCystic Fibrosis - Progress in phase 2 clinical trial of cystic fibrosis drug candidate reportedDengue Epidemic - Anticipating emergence/preventing spread reduces effects of dengue epidemicsDengue Fever - Ultrasound assists in diagnosis of dengue feverDengue Virus Vaccine - DNA vaccine induces protective antibodies against dengue virusDepression - Study found profound morning elevations of plasma IL-6 in depressed patientsDiabetes Complications - Scale measuring fear of complications in type 1 diabetes developedDiabetes Control - Pager-sized monitor for diabetes control receives FDA clearanceDiabetes Epidemiology - Diabetes management in San Diego's Chamorro community examinedDiabetes Therapy - Barriers to diabetes education in urban patients presentedDiabetes Therapy - U.S. FDA approves LevemirDiagnostics - U.S. FDA grants 510(k) clearance for blood screening controlsDiagnostics - U.S. FDA grants clearance for immunoassay for diagnosing venous thrombembolismDiet & Nutrition - FDA review period extended for chromium picolinate diabetes-related petitionDrug Delivery - Licorice root treatment in medicated disc for canker sores introducedDrug Development - Allon files IND to begin clinical trials for second product AL-208Drug Development - Botox to be studied as potential headache treatmentDrug Development - Phase III trial of Neurodex initiated for diabetic neuropathic painDrug Development - U.S. label changed for Iressa (gefitinib)Drug Safety - U.S. FDA reports on first meeting of Drug Safety Oversight BoardEbola Vaccine - Ebola virus L-domains characterized using VSV recombinantsEndometrial Cancer - Phase II clinical trial of cell-signaling protein inhibitor seeks patientsEnvironmental Health - Human health research and policy development near Great Lakes describedEpidemiology - Global trends in breast cancer incidence and mortality reported for 1973-1997Epilepsy - U.S. FDA approves Lyrica as epilepsy add-on treatment for partial onset seizuresEpilepsy - U.S. FDA approves new indication for TopamaxEtiology - Genetic analysis of common diseases in postmenopausal women is fundedFood Safety - Texas companies join to make beef genetic information available through webFungal Infection - Phototoxicity results from prolonged voriconazole therapyHIV/AIDS Coinfection - HIV-specific cytolysis/increased IL-10 associated w/ S. mansoni coinfectionHIV/AIDS Diagnosis - Efoora test rapidly detects HIV-specific antibodiesHIV/AIDS Drug Resistance - Mutations not associated with primary antiretroviral resistance in ChiliHIV/AIDS Epidemiology - Mathematical models make qualitative predictions about spread of HIV over timeHIV/AIDS Epidemiology - Mutagenetic trees describe accumulation of HAART-induced HIV mutationsHIV/AIDS Pathogenesis - Reports advance knowledge in HIV/AIDS pathogenesis researchHIV/AIDS Research - Report issued on phase 1/2 clinical trials for HIV/AIDS antiretroviral drugHIV/AIDS Therapy - FDA approves new therapy for HIV patients with advanced diseaseHIV/AIDS Treatment - U.S. FDA announces tentative approval of Lamivudine tabletsHIV/AIDS Vaccine - Enrollment in protease inhibitor program for HIV/AIDS patients to begin in fallHIV/AIDS Vaccine - Multiclade envelope HIV vaccine expands extent of virus neutralizationHIV/AIDS Vaccine - U.S. NIH center places HIV vaccine production order for phase 2 trialsHIV/AIDS Vaccines - Researchers publish new studies and findings in the area of HIV/AIDS vaccinesHIV/AIDS-Related Infection - Invasive S. pneumoniae infections declining in HAART eraHaemophilus Outbreak - Outbreak of invasive Haemophilus influenzae serotype A reportedHaemophilus Vaccine - Epitope of nontypeable H. influenzae protein plays role in immunityHealth Policy - Women's health suffers under welfare reform, study saysHealth Screening - Nurses perform as well as doctors in routine screening in STD clinicHealthcare Coverage - Chicago health leaders meet on state of the region's healthcare marketHeart Failure - FDA advisory committee recommends approval for BiDil for black patientsHeart Failure - FDA approves BiDil heart failure drug for black patientsHelicobacter Pylori - Probiotics improves tolerance to Helicobacter pylori eradication therapy
Hemoglobin - O-raffinose crosslinked hemoglobin lacks site-specificity in cavityHepatitis Vaccine - First sales of hepatitis A&B vaccine to Hunan Province, China CDC announcedHerpes Zoster - Varicella vaccine does not increase incidence of herpes zosterHerpesvirus Epidemiology - Human herpesviruses-6 and -7 cause significant neurological morbidityHuman Herpesviruses - Valacyclovir decreases EBV prevalence in saliva but not HHV-6 and HHV-7Human Papillomavirus - Screening important to detect persistent infections seen in older womenHuman Papillomavirus Vaccine - HPV-16 vaccine elicits broad cytokine response in whole bloodInfant Abuse - Early experience, not genetics, key factor in intergenerational infant abuseInfection Control - Guidance on public reporting of healthcare-related infections releasedInfectious Disease - Serum IgG mediates mucosal immunity against rotavirus infectionInfluenza - Production range for Fluvirin vaccine revisedInfluenza Vaccine - Factors influencing influenza vaccination in elderly reportedInfluenza Vaccine - Influenza vaccination recommended for HIV-1-infected patientsInfluenza Vaccine - Standing orders in ambulatory setting increases influenza vaccine usageInformation Technology - Company helps U.S. FDA identify online pharmacy misrepresentationInformation Technology - Device maker initiates worldwide physician communications on safety informationInformation Technology - U.S. FDA-compliant content management software for pharma, biotech use launchedIsotretinoin - Accutane SMART Program may not reduce pregnancy during isotretinoin useKidney Disease - FDA clearance received for Allient Sorbent Hemodialysis SystemLead Poisoning - Improved strategies to prevent childhood lead poisoning reportedLegionella Pneumophila - Sequence-based L. pneumophila typing concordant and discriminatoryLeishmaniasis Vaccine - DNA vaccine protects against Leishmania donovani Leukapheresis - Magnesium supplementation does not reduce side effects of leukapheresisListeria Monocytogenes - Cell-to-cell spread facilitates L. monocytogenes mom-to-fetal transmissionLiver Cancer - Data advance knowledge in liver cancer researchLiver Failure - U.S. NIH SIBR grant awarded for study of stem cell therapeutics in liver diseaseMMR Vaccine - Eliminating MMR immunizations does not decrease autism incidenceMalaria - Babies born from malaria-infected mothers susceptible to malaria early in lifeMalaria - Further studies needed to determine accuracy of rapid malaria diagnostic testsMalaria Vaccine - P. falciparum surface protein P. vivax homologue characterizedMedical Devices - Defibrillator software upgrade notification for physician customers announcedMedical Devices - International regulatory approvals granted for 2 resuscitation productsMedical Devices - Medical device company prepares to launch oxygen alert systemMedical Devices - Medical device company receives FDA approval for its high flux filterMedical Devices - Panel to recommend physician and patient communication guidelines for devicesMedical Devices - SmartStep launched for improved gait rehabilitationMedical Informatics - Record linkage protocol for diabetes registry at health center reportedMercury Poisoning - Loss of IQ due to mercury poisoning is economic productivity loss to U.S.Mergers & Acquisitions - Agreement makes RFID products available through healthcare supply servicesMergers & Acquisitions - Pharma company to acquire Vicuron PharmaceuticalsMetabolic Syndrome - New findings in metabolic syndrome describedMycobacterium Avium - M. avium enters state of metabolic dormancy in response to starvationMycobacterium Bovis - Tuberculosis in animals and humans reviewedMycobacterium Tuberculosis - M. avium subsp. paratuberculosis rapidly detected/typed from broth culturesMycobacterium Tuberculosis - Development of antitubercular drugs against persistent bacilli is neededMycobacterium Tuberculosis - HemZ is essential for heme biosynthesis in Mycobacterium tuberculosis Mycobacterium Tuberculosis - Immunity to infection with Mycobacterium tuberculosis is influenced by ageMycobacterium Tuberculosis - Transmembrane TNF provides acute control of M. tuberculosis infectionMycobacterium Tuberculosis - W-Beijing MTB strains identified with targeted IS6110 fingerprints hybridizationMyelodysplastic Syndromes - U.S. FDA grants priority review for REVLIMIDNecatoriasis Vaccine - Hookworm calreticulin is potential vaccine candidate for necatoriasisNewcastle Disease Vaccine - Existing vaccines protect chickens against Newcastle disease outbreakNocardiosis - Underlying diseases common in patients with nocardiosisObesity Genomics and Genetics - Peptide YY and Y2 receptor genes linked to obesity in Pima Indian menObstetrics - Pomegranate juice for moms may help babies resist brain injuryObstetrics - Recent findings illuminate research in obstetricsPatents - Biopharm company associated with U of Texas awarded additional Advexin patentPediatric Vaccine - Immunogenicity of vaccines in Asian infants born in U.K. reportedPersonnel - Mechanical heart device company names John J. Vajda VP of manufacturingPneumococcal Vaccine - Multiple pneumococcal vaccinations do not increase adverse reactionsPoisoning - Guidelines aid centers in managing patients who have ingested beta-blockersPoliovirus - Cloning system mass produces virus-binding protein specific for poliovirus-1Post-Traumatic Stress Disorder - Mental health of Kosovar Albanian humanitarian aid workers examinedProduct Recall - Guidant recalls certain defibrillatorsProstate Cancer - Phase III enrollment complete in Provenge trial for early-stage prostate cancerPseudomonas Aeruginosa - Mab against P. aeruginosa protective against fatal pseudomonas sepsisPseudomonas Aeruginosa - Substance P regulates NK cell IFN-gamma production/resist to P. aeruginosa Public Health - Perspectives on using scientific knowledge for public health presentedPublic Health - Surveillance of hazardous substance emergency events describedRespiratory Syncytial Virus - Group A RSV isolates from Argentina have more genetic variability than group BRotavirus Gastroenteritis - G9 is predominant genotype in pediatric rotavirus gastroenteritis in BelgiumSARS Coronavirus - Rolling circle amplification test rapid/sensitive for SARS coronavirus detectionSARS Outbreaks - Recent findings illuminate research in SARS ouTBreaksSARS Vaccine - RNA interference inhibits SARS-CoV antigenSaccharomyces Cerevisiae - Saccharomyces cerevisiae fungemia is an emerging infectious diseaseSepsis Therapy - Dendritic cells encoding IL-10 used to treat sepsisSexual and Reproductive Health - Pharma company received action letter from U.S. FDA for contraceptive implantSmoking - Association of tooth loss with disease risk was not confounded by smokingStaphylococcus Aureus - S. aureus Panton-Valentine leucocidin+ isolates from diverse backgroundsStem Cell Research - WNT1 and WNT3a promote expansion of melanocytes through distinct modes of actionStem Cell Transplantation - Clinical sequelae following microbially-contaminated SC infusions are rareStreptococcus Infection - Wound care team transmits group A streptococcal nosocomial transmissionStreptococcus Vaccine - COPD azithromycin therapy after Streptococcus vaccine reportedStress Urinary Incontinence - Phase 2 clinical study of oral drug for stress urinary incontinence approvedTransfusion Medicine - U.S. FDA grants priority review for Exjade for chronic iron overloadTuberculosis - Children require higher INH dose to achieve concentrations comparable to adultsTuberculosis - Gestational multidrug-resistant tuberculosis therapy not toxic among childrenTuberculosis - High-resolution CT detects activity of suspected smear negative pulmonary TBTuberculosis Risk Factors - Risk of TB for children in contact with infected adults reportedTuberculosis Vaccine - M. tuberculosis 19-kDa lipoprotein eliminates BCG protectionTuberculosis Vaccine - Mucosal delivery of ESAT-6 induces cell-mediated responses in lungUmbilical Cord Blood Banking - Semiautomated RBC depletion system saves time/improves cell recoveryVaricella Vaccine - Disparities exist in varicella vaccine coverage in CanadaVaricella Zoster Virus - VZV reactivates following discontinuation of aciclovir prophylaxis for HSCTVirology - Parvovirus B19 transmission caused by factor VIII concentrateVirology - Protein from the open reading frame 3 gene generates hepatitis E infectionWater-Borne Illness - Genetic diversity of noroviruses in sewage water examinedWater-Borne Illness - Systems approach to water-borne disease outbreak study describedYellow Fever - Fragment of yellow fever virus may hold key to safer vaccine
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