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Human Herpesviruses

Valacyclovir decreases EBV prevalence in saliva but not HHV-6 and HHV-7

Published in Medical Letter on the CDC and FDA, July 24th, 2005

Valacyclovir decreases the prevalence of Epstein-Barr virus in the saliva, but not human herpesvirus-6 and HHV-7.

According to a study from the United States, "Human herpesviruses (HHVs) are ubiquitous pathogens that intermittently reactivate from latency. Transmission is believed to be facilitated by their frequent appearance in saliva.

"This study sought to understand the factors that influence the appearance of these viruses in saliva by examining the prevalence, pattern, and quantity of all eight HHVs in saliva of immunocompetent adults with a history of recurrent oral herpes simplex virus (HSV) infections following dental treatment and antiviral...

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