Medical Letter on the CDC & FDA
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Human Papillomavirus
Gene expression profile of cervical cells harboring HPV-16 reported
July 24th, 2005
Scientists report the results of gene expression profiling of dysplastic differentiation in cervical epithelial cells harboring human papillomavirus 16 (HPV-16) in a recent issue of the journal Genomics. According to a study from the United States, "Molecular events occurring with high-risk human papillomavirus (HPV)-associated dysplastic differentiation of cervical epithelial cells are largely unknown. This study used differential display PCR to identify expression changes between nondifferentiating monolayer and differentiated organotypic (raft) cultures of W12 keratinocytes. These cells were originally derived from a clinical biopsy of HPV 16-positive...
Source: Medical Letter on the CDC & FDA (2005-07-24)
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