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Chlamydiosis

Azithromycin should be effective against IFN-gamma-induced persistent infection

Published in Medical Letter on the CDC and FDA, July 24th, 2005

Researchers predict that azithromycin should be effective against interferon-gamma-induced persistent Chlamydia trachomatis infection.

"Chlamydia trachomatis is responsible for clinically important chronic inflammatory diseases of humans, including trachoma and pelvic inflammatory disease. Persistent infection of mucosal sites may contribute to the development of these chronic inflammatory diseases. Standard clinical therapy results in satisfactory cure rates of acute infections; however, chronic infection associated with persistence has been suggested to be less responsive to antibiotic therapy," wrote N. Reveneau, U.S. National Institute of Allergy and...

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