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Coccidioidomycosis Vaccine
Immune response of vaccinated mice to Coccidioides investigated
July 24th, 2005
Investigated report the immune responses of vaccinated and non-vaccinated mice to Coccidioides posadasii infection in a recent issue of Vaccine. "An immunogenic, recombinant protein of the fungal respiratory pathogen, Coccidioides posadasii, was previously identified as a beta-1,3-glucanosyltransferase homolog (Gel 1) and shown to confer protection to C57BL/6 mice against coccidioidomycosis. "However, little is known about the nature of the humoral and cellular immune responses of these vaccinated mice to intranasal infection with a lethal inoculum of C. posadasii spores compared to non-immune control animals," scientists...
Source: Medical Letter on the CDC & FDA (2005-07-24)
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