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Medical Letter on the CDC & FDA

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Cystic Fibrosis



Progress in phase 2 clinical trial of cystic fibrosis drug candidate reported



July 24th, 2005

Inspire Pharmaceuticals, Inc. (ISPH) announced recent developments in its cystic fibrosis (CF) program.

Inspire has completed more than 50% of target enrollment in its ongoing phase 2 safety study, which is a double-blind, randomized comparison of 2 doses of denufosol tetrasodium (INS37217 Respiratory) to placebo in 72 patients with CF at 18 clinical centers across the United States.

This second phase 2 trial is being conducted in order to gain a greater understanding of safety and tolerability of denufosol in a broader population of CF patients, including patients with lower lung function and patients using antibiotics and other therapeutics,...


Source: Medical Letter on the CDC & FDA (2005-07-24)

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