Medical Letter on the CDC & FDA
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Depression
Study found profound morning elevations of plasma IL-6 in depressed patients
July 24th, 2005
Major depression is associated with significant diurnal elevations in plasma interleukin-6 levels, a shift of its circadian rhythm, and loss of physiological complexity in its secretion. "Major depressive disorder (MDD) is associated with increased risk for premature coronary heart disease and bone loss. Single-time measurements of plasma IL-6, a good predictor of future risk for both cardiovascular disease and osteoporosis, revealed significant elevations in depressed patients," scientists in the United States report. S. Alesci and colleagues of the U.S. national Institutes of Health wrote, "The objective of [our] study was to rigorously compare...
Source: Medical Letter on the CDC & FDA (2005-07-24)
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