Epilepsy
FDA approves new indication for Topamax as initial monotherapy
Published in Medical Letter on the CDC and FDA, August 7th, 2005
Effectiveness was demonstrated in a controlled trial in patients with epilepsy who had no more than 2 seizures in the 3 months prior to enrollment. Safety and effectiveness in patients who were converted to monotherapy from a previous regimen of other anticonvulsant drugs have not been established in controlled trials.
"Antiepilepsy medications, or neuromodulators, are selected...
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