Medical Letter on the CDC and FDA

Anthrax - Complement depletion renders mice sensitive to Bacillus anthracis

HIV/AIDS Vaccine - Impact of HIV genetic diversity on vaccine development reviewed

Lyssaviruses - Rabies biologics are effective against some lyssaviruses from Eurasia

Measles Virus - Amino acid variations affecting measles virus replication identified

Outbreaks - Seed source identified for E. coli outbreaks linked to sprouts

 Hemophilus ducreyi -  H. ducreyi dsrA mutant killed by normal human serum initiated by IgM binding

Adverse Drug Reactions - Importance of reporting suspected adverse drug reactions emphasized

Adverse Drug Reactions - Study reveals consumers willing to take medication with risks similar to Vioxx

Allergy & Immunology - Company announces rapid, expanded enrollment in ragweed allergy pediatric trial

Allergy Medicine - Labeling food allergens can be a struggle

Allergy Medicine - Sesame allergy is significant, serious and growing globally

Anthrax Vaccine - Oral spore vaccine based on Bacillus anthracis antigen developed

Antimicrobial Resistance - Susceptibility testing method to determine bacterial MICs standardized

Antimycobacterial Drug Development - Oxadiazolone derivatives have antimycobacterial activity

Aspergillosis Therapy - Voriconazole less expensive than amphotericin B for aspergillosis

Atrial Flutter - Company submits PMA for atrial flutter treatment

Avian Influenza - International health entity stresses threat from Avian influenza has not ebbed

Benign Prostatic Hyperplasia - FDA approves Cooled ThermoCath 4.5+ treatment catheter

Biotechnology - Health professionals hold positive attitudes toward biotechnology

Biotechnology - Jeff Myers named vice president of government affairs

Bioterrorism - Groups work to develop vaccine to reduce effects of ricin toxin

Bladder Cancer - Bladder cancer test receives marketing approval in Japan

Business & Finance - Biopharma company announced financial results

Business & Finance - Biosensor, microproccessor developer completes reverse acquisition transaction

Business & Finance - Single-use medical devices company listed on new Russell Microcap Index

Business Update - Cell-based regenerative therapies developer changes name to Cytori Therapeutics

Business Update - Centene Corp. subsidiary expected to expand operations in Texas

Business Update - Company gets clearance for its Dimension Vista 1500 integrated system

Business Update - Company to seek VA contracts for pharmacy robotic technology

Business Update - Radiofrequency ablation systems company appoints audit firm

CNS Lymphoma - Necrotizing vasculopathy diagnosed in primary CNS lymphoma

Cardiology - U.S. FDA grants full approval to conduct a pivotal trial of the Jarvik 2000

Cardioprotection - Cardiac GCA prevents cardiac remodeling by inhibiting calcineurin-NFAT pathway

Cardiovascular Research - Dedicated investment in CV outcomes research could improve care in the US

Chickenpox Vaccine - Oka/GSK attenuated varicella vaccine prevents chickenpox in clinical practice

Clinical Trials - Ghrelin agonist shows selectivity profile in treating gastrointestinal disorders

Clinical Trials - SPA process completed for paclitaxel formulation clinical trial in breast cancer

Coccidioidomycosis - Precipitation influences incidence of coccidioidomycosis outbreaks

Compliance - Ophthalmic products developer reports on latest communications with U.S. FDA

Dengue Fever - Cemetery is source of dengue vector

Diabetes Education - Predictors of compliance with diabetes education in Turkey reported

Diabetes Prevention - Six healthy habits program helps prevent diabetes

Diabetes Therapy - Diabetes patient-oriented evidence that matters on Internet studied

Diabetes Therapy - Metformin versus conventional approach for type 2 diabetes compared

Diagnostics - U.S. FDA grants 510(k) clearance for infectious mononucleosis rapid tests

Disease Associations - HIV/HCV co-infection associated with diabetes

Disease Management - Telephone communications credited with improving health

Drug Abuse - Wife influences husband's marijuana use during first year of marriage

Drug Development - Agreement reached with U.S. FDA for renzapride phase III trial

Drug Development - IGIV selected by company as first therapeutic protein product for development

Drug Development - Phase II trial of Hematide for anemia begins

Drug Development - Positive opinion granted for Humira in Europe for rheumatoid arthritis

Drug Development - Product promotes healing in venous stasis ulcers

Drug Development - Sotradecol injection for varicose veins launched in U.S. market

Drug Development - U.S. FDA grants approval for Allegra capsules

Drug Importation - Professional society warns against discount injectables bought offshore

Endocarditis - AHA publishes statement on infective endocarditis

Environmental Health - Highest concentration of ground water contamination found in northeast U.S.

Epidemic Surveillance - Method rapidly identifies/types respiratory pathogens for epidemic surveillance

Epidemiology - Abortions/neonatal mortality associated with T. evansi infection in camels

Epidemiology - In utero factors may affect cancer risk differently among ethnic groups

Epilepsy - Seizure-focused foundation lauds U.S. FDA approval of monotherapy for epilepsy

Finance - Biotech company reports Q2 GAAP EPS of $0.46, non-GAAP EPS of $0.57

Finance - Diabetes-focused biotechnology company returns to independent status

Finance - Pharmaceutical company added to 2005 Russell Indices

Food-Borne Illness - Sources of variability of acrylamide levels in cracker model identified

Food-Borne Illness - What we don't know about handling food can hurt

Gastrointestinal Tuberculosis - Gastrointestinal TB not an uncommon diagnosis in northeastern Parisian area

Generic Drugs - Pharma company gains approval to market Metformin XL Tablets

Gentamicin - Method to measure gentamicin in bovine fluids and tissues developed

Grants - Michigan U health system receives $10 million NIA grant for Alzheimer research

Gynecology - Microsatellite profiles categorize endometrial cancers

HIV/AIDS & Dengue Fever - Dendritic cell precursors are permissive to dengue virus and HIV infection

HIV/AIDS Diagnosis - Efoora is rapid test for detection of HIV-specific antibodies

HIV/AIDS Epidemiology - Decrease in drug resistance levels of HIV epidemic can be bad news

HIV/AIDS Epidemiology - Laboratory method aids estimation of HIV-1 incidence

HIV/AIDS HAART - Risk of triple-class antiretroviral drug failure declining in Denmark

HIV/AIDS Infection - HIV infection in children of paid plasma donating community reported

HIV/AIDS Pathogenesis - Resting naive CD4+ cells massively infected/eliminated by X4-tropic SHIV

HIV/AIDS Prevention - Study shows barriers to HIV vaccine acceptance

HIV/AIDS Prevention - Why were the HIV prevention trials in commercial sex workers abandoned?

HIV/AIDS Risk Behavior - No difference in risk behavior when partner is aware of HIV serostatus

HIV/AIDS Risk Factors - Adolescent groups identified as at most risk for acquiring HIV infection

HIV/AIDS Stigma - Nine-item scale measures AIDS-related stigma in South Africa

HIV/AIDS Transmission -  Trichomonas vaginalis promotes sexual transmission of HIV-1

HIV/AIDS Vaccine - AIDS vaccine development reviewed

HIV/AIDS Vaccine - Adenoviral gene delivery for HIV-1 vaccination reviewed

HIV/AIDS Vaccine - Cross-reactivity of anti-HIV immune responses of major HIV-1 clades reported

HIV/AIDS Vaccine - Lentiviral vector encoding Gp41-derived fusion inhibitor suppressed HIV

HIV/AIDS Vaccine - Method to measure HIV vaccine efficacy ethically presented

HIV/AIDS-Associated Infection - Some HIV protease inhibitors can inhibit Encephalitozoon intestinalis growth

HIV/AIDS-Tuberculosis Coinfection - TB incidence remains high despite isoniazid prophylaxis in HIV-infected persons

Healthcare Coverage - DoD-sponsored health plan reports high enrollee satisfaction