Medical Letter on the CDC and FDA

Anthrax Vaccine - Adverse events reported by participants in CDC anthrax program reviewed

Fetal Loss Risk Factors - Elevated factor VII is risk factor for recurrent fetal loss

Hepatocellular Cancer - SEN virus infection not major cause of hepatocellular carcinoma

Malaria Diagnosis - Malaria screening and treatment of refugees from Cambodia described

Poliovirus Genomics and Genetics - Genomic analysis of vaccine-derived poliovirus strains reported

Acinetobacter Baumannii Outbreak - Carbapenem-resistant Acinetobacter baumannii cause of hospital outbreak

Adverse Drug Reaction - Agency issues public health advisory on transdermal fentanyl patches

Adverse Drug Reaction - Four reported deaths prompt warning about Mifeprex

Allergy & Immunology - FDA OKs reformulated Clarinex orally disintegrating prescription antihistamine

Alzheimer Disease - FDA panel votes 5-2 against kit form of NTP test

Amyotrophic Lateral Sclerosis - FDA wants more information about planned phase II clinical trial for ALS

Malaria Vaccines - Recent findings illuminate research in malaria vaccines

Anthrax - Researchers describe findings in anthrax studies

Anxiety Disorder - Benzodiazepines and anxiety disorders reviewed

Aspergillosis - Pulmonary zygomycosis distinguished from invasive pulmonary aspergillosis

Asthma - "Stop and go" traffic increases infant wheezing

Attention Deficit Hyperactivity Disorder - U.S. Patent office sends allowance for attention deficit, hyperactivity drug

Behavioral Medicine - Health, responsibility, and choice of the public examined

Malaria Vaccines - Reports add new data to malaria vaccines research

Biotechnology - FDA requests additional data on PULMINIQ

Bioterrorism - Walter Reed Army institute, pharmaceutical company sign research agreement

Business & Finance - Pharmaceutical company announces second-quarter 2005 earnings per share

Business & Finance - Pharmaceutical company reports first quarter financial results

Business Update - Company gets EN: ISO 13485:2003 certification, renewed Canadian certifications

Business Update - Company provides update on Myopore Rx steroid lead status with FDA

Business Update - Company to amend EP-2104R clinical trial protocols

Business Update - Manufacturing agreement signed for Ergothioneine

Business Update - Pharmaceutical firm receives inspectional observations from U.S. FDA

Business Update - U.S. Defense Department awards contract for extremity MRI systems

Cancer Research - Clinical trial for treatment of chemotherapy-induced anemia on hold

Cancer Vaccines - Modeling and simulation of cancer immunoprevention vaccine presented

Chickenpox Vaccine - Varicella vaccination of children in the United States evaluated

Childhood Immunization - U.S. vaccination rates surpass Healthy People 2010 goal

Childhood Obesity - Researchers provide details of new studies and findings in the area of childhood obesity

Clinical Trials - Challenges in systematic reviews that assess treatment harms outlined

Clinical Trials - IDE submitted for vascular closure system in preparation for clinical trial

Clinical Trials - Postoperative analgesia for infusion found to be effective, company announces

Cocaine Vaccine - Glyceride adjuvant induces protective antibodies against cocaine

Coccidiosis Vaccines - Reports add new data to coccidiosis vaccines research

Cognitive Development - Must-NOT-see TV: Toddler development hurt by TV viewing

Colon Cancer - Market for colorectal cancer screening by endoscopy in U.S. reported

Complementary and Alternative Medicine - China herbal company plans to seek FDA approval for traditional herbal medicines

Corynebacterium Infection - High prevalence of ulcerative posthitis in rams associated with legume-rich diet

Critical Care Medicine - Carvedilol reverses MDMA-induced hyperthermia

Cyclospora Cayetanensis - Flow cytometry detects Cyclospora cayetanensis oocytes in fecal specimens

Deafness - Epidemiological study of mumps deafness in Japan performed

Depression - FDA approves VNS therapy for treatment-resistant depression

Depression Therapy - Efficacy and safety of antidepressants in youth depression reviewed

Diabetes Risk Factors - Asian Indians in United States have relatively high diabetes risk

Diabetes Therapy - New research in the area of diabetes therapy detailed

Diagnostics - Respiratory pathogens rapidly identified/typed for epidemic surveillance

Diagnostics - TaqMan-based 1-step PCR assay rapid and sensitive for norovirus detection

Drug Development - Drug developer sets $15 million financing, renin inhibitor collaboration

Drug Development - Emezine NDA accepted for review by U.S. FDA

Drug Development - Final approval granted for hydrochlorothiazide capsules 12.5 mg

Drug Development - Hepatitis C drug discovery collaboration expanded

Drug Development - IND filed with U.S. FDA for pivotal phase III trial of antifungal agent

Drug Development - Pharmaceutical company files ANDA for injectable anticancer drug

Drug Development - U.S. FDA grants clearance for Parallax Acrylic Resin with TRACERS-Ta

Drug Development - U.S. NIH awards $1.49 million grant to prepare blood clot drug for human trials

Drug Safety - U.S. FDA requests opioid drug label changes from pharmaceutical company

Ebola - Agreement signed to evaluate Tarvacin for hemorrhagic disease

Environmental Health - Abundance and diversity of viruses in six Delaware soils determined

Environmental Health - CDC releases extensive survey of Americans' exposure to environmental chemicals

Environmental Health - Influence of erythromycin A on aquaculture microbes examined

Epilepsy - FDA approval for VNS therapy provides potential 2-in-1 treatment for epilepsy

Erectile Dysfunction - Superoxide anions in penis impair erectile function in diabetes

Finance - Healthcare products corporation reports financial results for Q2 2005

Finance - Medical products company reports financial performance for second quarter 2005

Finance - Minnesota device company reports Q2 sales of $7.2 million

Finance - Vascular device company announces profitability and record Q2 2005 results

Food Safety - Canadian marketing approval received on DNA IHNV virus vaccine for salmon

Food-Borne Illness - System finds outbreaks sooner, faster

Generic Drugs - U.S. FDA grants tentative approval of generic antihistamine tablet

Genetically Engineered Food - Scientific concerns about genetically engineered food reviewed

HIV Therapy - Pharma company receives U.S. FDA approval for Zidovudine Tablets

HIV/AIDS Diagnostics - Evolving technologies for HIV diagnostics benefit resource-limited areas

HIV/AIDS Diagnostics - Low-cost assays available to monitor HAART in resource-poor settings

HIV/AIDS Diagnostics - Total lymphocyte count helps predict low CD4 count in low-resource setting

HIV/AIDS Drug Development - Fermented P. tinctorium Aiton extract suppresses acute HIV-1 infection

HIV/AIDS Drug Development - Measles virus inhibits HIV-1 replication in lymphoid tissues

HIV/AIDS Education - Individuals in Iran have fairly good AIDS-related knowledge

HIV/AIDS Epidemic - HIV-1B and C subtypes have different epidemic potentials

HIV/AIDS Epidemiology - HIV-1 subtype C/HIV-2 subtype A are major subtypes circulating in south India

HIV/AIDS GBV-C Coinfection - Prevalence of Gb virus C in perinatally HIV-infected children is small

HIV/AIDS Pathogenesis - SEN virus seroprevalence in HIV+ patients linked to HIV-replication

HIV/AIDS Pediatrics - HIV-infected children have poorer qualitative antibody response to PnCV

HIV/AIDS Pediatrics - Population-specific infant mortality rates guide HIV and infant feeding policy

HIV/AIDS Prevention - Media can help increase HIV testing

HIV/AIDS Research - HAART suppresses viral load in macaques infected with RT-SHIV

HIV/AIDS Therapy - FDA grants fast track status for investigational HIV protease inhibitor

HIV/AIDS Tuberculosis Coinfection - HAART plus TB DOT strategy improves outcome of HIV/TB coinfected patients

HIV/AIDS Vaccine - BCG is a potential vehicle for use in HIV vaccine development

HIV/AIDS Vaccine - DNA vaccines expressing different SIV antigens decrease viremia

HIV/AIDS Vaccine - Effect of CD8+ lymphocyte depletion on SIV containment examined

HIV/AIDS Vaccine - Single round PCR and cloning method used to develop HIV vaccine

HIV/Hepatitis C Coinfection - Pegylated interferon alpha-2a effective/well-tolerated in HIV/HCV coinfection

HIV/Tuberculosis Coinfection - Risk of resistance in HIV/TB coinfection depends on rifampin dosing schedule

HLA-A Typing - Sequencing strategy reliable and efficient for high-resolution HLA-A typing

Haemophilus Vaccine -  H. influenzae b (Hib) vaccination increases Hib genetic diversity

Haemophilus Vaccine - Infant immunization with Haemophilus influenzae re-established

Haemophilus Vaccines - New data illuminates research in haemophilus vaccines

Healthcare Coverage - U.S. CMS approves benefits company's managed care coverage expansion

Heart Disease Risk Factors - Brisk walking increases fitness and lowers cardiovascular risk

Hemophilus Influenzae Outbreaks - Invasive Hemophilus influenzae serotype outbreak has occurred in infants