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Mycobacterium Tuberculosis

 M. tuberculosis remains viable despite treatments for DNA extraction

Published in Medical Letter on the CDC and FDA, September 4th, 2005

Mycobacterium tuberculosis remains viable despite the use of treatments for DNA extraction.

"DNA fingerprinting of Mycobacterium tuberculosis by IS6110 restriction fragment length polymorphism analysis requires substantial high-quality DNA," investigators in Canada report.

"We demonstrated that, despite extraction treatments that might be expected to inactivate this organism, M. tuberculosis remained viable during this process," wrote W. Somerville and colleagues at Montreal General Hospital.

The authors concluded, "These data suggest that the extraction of M. tuberculosis DNA should be performed within...

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