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Toxicology

Structure-activity relation analysis in food contact program described

Published in Medical Letter on the CDC and FDA, September 11th, 2005

Scientists describe the use of structure-activity relationship analysis in the food contact notification program in a recent issue of Regulatory Toxicology and Pharmacology.

According to a study from the United States, "Food contact substances (FCS) include polymers, paper and paperboard, and substances used in their manufacture, which do not impart a technical effect on food. Moreover, FCSs are industrial chemicals generally consumed at dietary concentrations (DC) of <1 mg/kg food (ppm), and more commonly at <0.05 ppm (50 ppb), in the daily diet. As such, many industrial chemicals have been analyzed for toxicological concern, some of which may share...

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